The diagnostic value of endometrial biopsy in many gynsecologieal conditions particularly in the investigation of causes for sterility in women, menstrual disturbances, endometrial response to various hormones, infections and malignant disease is being recognized and the histological appearances accepted as more dependable now than was the case in the past. Along with other morbid histology mat...

BACKGROUND The early molecular detection of the dysplasia-carcinoma transition may enhance the strength of diagnosis in the case of colonic biopsies. Our aims were to identify characteristic transcript sets in order to develop diagnostic mRNA expression patterns for objective classification of benign and malignant colorectal diseases and to test the classificatory power of these markers on an i...

The fine needle aspiration biopsy (FNAB) is a quick, simple, safe, painless and inexpensive method. It is of the utmost importance in the preoperative diagnostics of tumours.1 The diagnostic reliability of the method is good. It enables us to classify tumours as malignant or benignant in almost 100% cases and to further specify the type of the tumour in 80-98% of cases.2 Serious side effects (p...

Formalin fixing with paraffin embedding (FFPE) has been a standard sample preparation method for decades, and archival FFPE samples are still very useful resources. Nonetheless, the use of FFPE samples in cancer genome analysis using next-generation sequencing, which is a powerful technique for the identification of genomic alterations at the nucleotide level, has been challenging due to poor D...

Introduction The established and large-scale use of certain synthetic chemicals, especially pesticides, has led to their absorption and deposition in animals and man. The authors' interest lay in the pharmacodynamics of the synthetic organochlorine insecticide, dieldrin, which is primarily deposited and stored in the body lipid. Its study required repeated measurements of the deposition of this...

Archival theory comprises the ideas about the nature of archival material as they have developed overtime, confronted with the record reality of different cultures and juridical contexts. It constitutes the core of archival science. Archival science comprises also the principles and methods for the control and preservation of archival material (i.e., archival methodology), the analysis of archi...

A total of 300 gastric biopsy samples and 50 Helicobacter pylori isolates were collected from Ethiopian adult dyspeptic patients. The vacA and cagA genes were detected in 90 and 79% of biopsy specimens, respectively, and in 100 and 87% of clinical isolates, respectively. Both genes were detected in 84% of the gastric biopsy samples and in 87% of the clinical isolates. Among vacA genotypes, the ...