OBJECTIVE Arterial stiffness may be involved in the impairment of the arterial baroreflex. In the present study the associations between arterial stiffness and cardiovagal baroreflex sensitivity (BRS) and between BRS and postural blood pressure (BP) changes were investigated within the framework of the Rotterdam Study. METHODS Arterial stiffness was determined by aortic pulse wave velocity an...

Stroke is the second leading cause of mortality and morbidity worldwide. Early intervention is of great importance in reducing disease burden. Since the conventional risk factors cannot fully account for the pathogenesis of stroke, it is extremely important to detect useful biomarkers of the vascular disorder for appropriate intervention. Arterial stiffness, a newly recognised reliable feature ...

Arterial stiffness is a well-known predictor of arteriosclerotic vascular disease. One index of arterial stiffness was the pulse wave velocity (PWV). But, it is known that PWV depends on the blood pressure at measuring time. Cardio-ankle vascular index (CAVI) is derived from stiffness parameter beta, and reflects the stiffness of the artery from the origin of the aorta to the ankle as a whole. ...

BACKGROUND Increased arterial stiffness assessed by carotid-femoral pulse wave velocity (CFPWV) and central augmentation index (AIx), has been associated with a worse cardiovascular prognosis and increased prevalence of angiographic coronary artery disease (CAD). Obesity, a well-recognized cardiovascular risk factor, has been related to increased arterial stiffness, although not consistently. T...

INTRODUCTION AND AIMS Patients with periodontitis have a higher risk of cardiovascular diseases, although a causal relationship between these conditions remains unclear. Arterial stiffness is considered a marker of arteriosclerosis and a risk factor for cardiovascular diseases. A systematic review of the literature on clinical studies using pulse wave velocity (PWV) to assess arterial stiffness...

Arterial stiffness has been proposed as an indicator of vascular aging. We aimed to examine this concept by analyzing associations of arterial stiffness with age, subjective and objective measures of physical functioning, and self-reported functional limitation. We measured aortic pulse wave velocity by applanation tonometry among 5392 men and women aged 55 to 78 years. Arterial stiffness was s...

Varol and Ozaydin raise an important question about the effects of antihypertensive drugs and statins on arterial stiffness. In fact, antihypertensive drugs reduce large arterial stiffness, partly independently of blood pressure reduction, suggesting specific pharmacological effects on arterial remodeling. Furthermore, statins and other cholesterol-reducing agents have been shown to have benefi...

Objective: Depression and anxiety are associated with both subclinical and clinical cardiovascular disease. Endothelial dysfunction, atherosclerosis, and inflammation are some of the underlying mechanisms. Pulse wave velocity (PWV) and augmentation index (AIx) are noninvasive markers for evaluation of arterial stiffness. The aim of this study was to examine the association between arterial stif...

PURPOSE Physical inactivity behavior at middle age or older is a major risk factor for cardiovascular disease. However, the effects of levels of habitual physical activity on arterial stiffness in elderly population remain unclear currently. Therefore, the purpose of this study was to demonstrate whether the effects of habitual physical activity could attenuate arterial stiffness in elderly ind...

High arterial stiffness is increasingly conceptualized as a cause of hypertension, in addition to being a consequence of long-standing high blood pressure. For instance, recent observations from the Framingham Offspring cohort suggest that increases in blood pressure and new-onset hypertension were antedated by higher arterial stiffness. A similar relation between vascular stiffness and later-l...