Cognition and communication deficits often prevent Traumatic Brain Injury (TBI) patients, who are otherwise functioning well, from returning to work. This study is focused on the exploration of the associations between known patient characteristics and measurable communication outcomes from speech-language pathology intervention. Furthermore, the adequacy of aphasia batteries as assessment tool...

INTRODUCTION: Pre-pectoral breast reconstruction is an emerging technique with potential benefits that include reduced pain, early patient recovery and no hyperanimation. There are studies reporting on clinical outcomes with pre-pectoral technique [PP] and comparing it to the dual plane technique [DP] in breast reconstruction. The goal of this study is to provide an early assessment of outcomes...

INTRODUCTION: Pre-pectoral breast reconstruction is an emerging technique with potential benefits that include reduced pain, early patient recovery and no hyperanimation. There are studies reporting on clinical outcomes with pre-pectoral technique [PP] and comparing it to the dual plane technique [DP] in breast reconstruction. The goal of this study is to provide an early assessment of outcomes...

We urgently need new therapies to improve outcomes after cardiac arrest. Initial studies typically target surrogate endpoints, and these studies help to inform subsequent larger trials that are powered to measure more patient-orientated clinical outcomes such as survival. The competing risk of death and premature assessment of neurological prognosis pose significant challenges to measuring thes...

OBJECTIVE To examine physician-assessed medical signs and patient-reported medical symptoms as correlates of 3 quality of life (QOL) outcomes in patients with systemic sclerosis (SSc): disability, pain, and psychosocial adjustment. METHODS One hundred fourteen patients with SSc underwent a comprehensive clinical examination including determination of skin thickening [Modified Rodnan Skin Scor...

INTRODUCTION Outcome measures of breast reconstruction have used panel assessment of photographs. This provides limited information to the assessor as these images are static.. The aim of this study was to assess whether the use of digital video was a valid assessment tool and to compare its use against photography. METHODS 35 patients post-reconstruction underwent photography, digital video ...

Aim and objectives: The aim of this study was to audit the success of treatment outcomes following assessment and treatment planning of anxious patients referred for conscious sedation. The outcome of treatment has a marked effect on ratings of its acceptability. Treatments associated with positive outcomes appear to be more acceptable than those associated with poor outcomes. Design: A standar...

OBJECTIVE To compare the relationship between clinical measures and patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA) treated with tofacitinib or methotrexate (MTX). METHODS In a phase 3 randomised controlled trial, patients (N=956) who were MTX-naïve or had received ≤3 doses were randomised and received tofacitinib 5 or 10 mg twice daily or MTX titrated to 20 mg/wee...