Background: There are several causes leading to male infertility, like oxidative stress, and nutritional deficiency of trace elements i.e., selenium and zinc. The Zinc is the following only to iron as the most abundant element in the body. Although, Zinc is found in red meat, white meat, fish, and milk; the World Health Organization (WHO) approximates that one-third of world population is defic...

Background: Oligoasthenospermia (OAS) is a condition characterized by low sperm count associated with low sperm motility. Medical treatment is not known in allopathic system for treatment of oligoasthenospermia. Homeopathic medicine is effective in more than 95% patients. Oxidative stress and decreased antioxidant levels have been projected as a potential factors involved in the pathophysiology...

BACKGROUND Low concentrations of nitric oxide (NO) are necessary for the biology and physiology of spermatozoa, but high levels of NO are toxic and have negative effects on sperm functions. Although several studies have considered the relationship between infertility and semen NO concentrations, no study on the effects of asthenospermia treatments such as oral zinc supplementation on concentrat...

Abstract Study question Is Next Generation Sequencing (NGS) an effective diagnostic tool for sperm abnormalities? Summary answer NGS male factor gene panel can be a potent discovering pathogenic variants linked to abnormalities. What is known already Male infertility, responsible half of infertility cases, often shows as absence or decreased count (azoospermia, criptozoospermia oligozoospermia)...

Background: Asthenozoospermia, a disorder of sperm motility, is a common cause of human male infertility and is found to play a role in approximately 19% of infertile patients. Epidemiological studies indicated a link between environmental pollutants, lifestyle changes, and dietary habits and infertility. In view of the fact that nutrition is coming to the fore as a major environmental factor, ...

objective: to evaluate the efficacy of in vitro sperm activation (isa) using non-liquefied versus liquefied asthenozoospermic semen samples for improvement of sperm parameters. materials and methods: fifty six oligoasthenozoospermic (oa) patients (age range: 22-44 years; mean: 32.089 years) were enrolled in this study. oa patients were classified according to type of infertility. also, duration...

Background: The generation of reactive oxygen species (ROS) in the male reproductive tract has become an actual concern because of their probable noxious effects, at high levels, on physical properties of sperm quality. ROS are extremely reactive oxidizing agents, which a member of the class of free radicals. It was found that uric acid can act as an essential water soluble antioxidant and ther...

STUDY QUESTION Does CatSper have a role in the achievement of human sperm motility and in the Progesterone (P)-induced acrosome reaction (AR)? SUMMARY ANSWER CatSper1 expression is associated with human sperm progressive motility and the P-induced AR; it may have a role in the pathogenesis of asthenozoospermia. WHAT IS KNOWN ALREADY Knockout mice for any of the Catsper family genes fail to ...