Pilocytic astrocytoma is a slow-growing brain tumor that occurs more often in children with a benign course and long clinical history compared to diffuse astrocytomas. Pilocytic astrocytomas may rarely show malignant transformation and radiotherapy plays a key role in the treatment of malignant transformation. In this study, we present a pilocytic astrocytoma case with no radiotherapy history a...

We report the MRI findings of an adult patient with a (rare in adults) biopsy-proven pilocytic astrocytoma with anaplastic features. Diffusion tensor imaging may potentially provide information on cell proliferation, vascularity, and fiber destruction, which can have implications for treatment and prognosis. In this case, tractography and fractional anisotropy maps demonstrated displacement of ...

Malignant glioma comprises glioblastoma [World Health Organization (WHO) grade IV], anaplastic astrocytoma (WHO grade III), mixed anaplastic oligoastrocytoma (WHO grade III) and anaplastic oligodendroglioma (WHO grade III). Diagnosis after biopsy or tumor resection is made according to the revised WHO classification. Prognosis depends on tumor grade and histology. Glioblastoma carries the worst...

Pilomyxoid astrocytoma (PMA) is a rare tumor that was previously classified as pilocytic astrocytoma (PA) because of similar histological features. [1] Compared with PA, PMA demonstrates more aggressive biological behavior, and was assigned to World Health Organization (WHO) α grade according to the 2007 WHO Classification. [2] PMA in the spinal cord is extremely rare. We documented probably th...

Pilocytic astrocytomas and meningiomas are benign, primary brain tumors that may involve the optic tract. Classically, the presence of a dural "tail" sign may differentiate a meningioma from other intracranial lesions. In this report, we describe a mass with the typical appearance of a clinoidal meningioma on magnetic resonance imaging (MRI) but postoperatively diagnosed as a pilocytic astrocyt...

A 32-year-old male presented with progressive pure amnesia caused by astrocytoma invading the bilateral medial temporal lobes. Methionine positron emission tomography demonstrated the extent of tumor invasion well. His memory impairment was partially improved by treatment for the astrocytoma. Lesion of the bilateral hippocampus causes memory impairment, but pure memory loss without other associ...

SUMMARY Antigens from a rat astrocytoma cell line were compared with those from normal rat liver and normal rat brain by the immunodiffusion and immunoelectrophoresis techniques. Antigens that appeared to be specific to the tumor cells were observed. Although these were predominantly in the soluble fraction, a small but distinct amount of the antigens were found to be membrane bound. The existe...

A case is reported of a 19-year-old male having right proptosis for 4 years because of a mixed meningioma and astrocytoma of the ipsilateral optic nerve. The sheath of this nerve is analogous to the leptomeninges, and neuroglial cells constitute the stroma of the nerve. Both meningioma and astrocytoma therefore can arise primarily in the optic nerve, and they may be combined in the same mass, f...

A simple and reproducible injection technique has been developed for inducing an in vivo experimental astrocytoma model in rats. Newborn rats were injected with a suspension of astrocytoma C-6 cells in doses ranging from 5 to 1 X 10 5 cells. The optimum dose of tumor cells was found to be between 10 4 and 10 5 cells, with a consistent 100% take rate seen above 1 X 10 4 injected cells. The injec...

Fahr's disease is a rare entity characterized by abnormal calcification in the bilateral basal ganglion regions and cerebellum. Concurrence of Fahr's disease with brain tumor is associated with an even lower incidence; the present study describes the fifth such case, in which a 32-year-old female presented with a 1-month history of headache and unsteady walking. Pathology and imaging studies re...