biotypes, serotypes and lysotypes of 38 yersinia isolated from 48 water samples were studied. these strains belonged to y.enterocolitica, y.frederiksenii, y.kristensenii and y. intermedia. except 23.7% of non-serotypable strains, ten different serotypes were isolated of which 0:6 and 0:10 kl were the most frequent. the serotypes 0:3, 0:8, 0:9 responsible for almost all registered cases of yersi...

Background & Objective: Meningiomas are the most frequently encountered primary non-glial tumors of the central nervous system (CNS). The Ki67 labelling index (Ki67LI) is a proliferation marker that may prove useful in determining the histological grade. This study aims at: 1) Studying the frequency, grade and histomorphological spectrum of meningiomas, 2) Evaluating 20 histolo...

Sialophorin, previously called gpL115, is the heavily sialylated surface protein that is defective in lymphocytes of Wiskott-Aldrich syndrome patients. Using the monoclonal antibody L10 as a probe, sialophorin expression was detected on isolated T lymphocytes and thymocytes, B cell lines, monocytes, neutrophils, and platelets, but not on erythrocytes, fibroblasts, and glioblastoma cells. This u...

Paraffin-embedded lung wedge biopsy specimens from 14 patients with pulmonary lymphomatoid granulomatosis (LYG) were analyzed using immunoperoxidase stains specific for T cell- and natural killer cell-associated antigens. Nine cases had a minor population of CD20+ large B-cells (B-cell LYG) amidst a background of CD3- and betaF1-immunoreactive T cells. In 8 of the 9 B-cell LYG cases, the majori...

Reprint requests to: Dr M J Saldana, Department of Pathology and Laboratory Medicine, Blum Building, 2nd Floor, Mount Sinai Medical Center, 4300 Acton Road, Miami Beach, Florida 33140, USA. It is generally agreed that the acquired immunodeficiency syndrome (AIDS) results from infection by the human immunodeficiency virus (HIV). The latter agent destroys primarily T helper lymphocytes and produc...

Mycosis fungoides (MF) is a relatively rare cutaneous T-cell malignancy. Only two cases of MF with marked eosinophilia have been reported. In addition, MF with concomitant squamous cell carcinoma (SCC) occurring in the site of MF has not been reported. The author reports herein a very rare case of MF in the plaque stage showing pronounced eosinophilic infiltration, folliculotropic pattern, and ...

Primary cutaneous follicle center lymphoma (PCFCL) is the most common B-cell lymphoma. The typical immunophenotype includes expression of both CD20 and BCL6, with majority cases lacking CD10, BCL2, characteristic t(14;18)/IGH-BCL2 rearrangement seen in systemic follicular (FL). Plasmacytic differentiation (PD) an uncommon finding FLs presents a diagnostic challenge when present, leading to pote...

Dopamine is a major neurotransmitter in the central nervous system, and its receptors are associated with a number of neuropathological disorders such as Parkinson's disease and schizophrenia. Although the precise pathophysiology of schizophrenia remains unknown, the dopaminergic hypothesis of the illness assumes that the illness results from excessive activity at dopamine synapses in the brain...

neuroleptic malignant syndrome (nms) is a rare fatal medical complication that occurs as a result of dopaminergic receptor blockage in the caudate at the termination of the nigrostriatal pathways (1), and may occur at any time following consumption of dopamine antagonists. this disorder also occurs in cases of sudden discontinuation of dopamine agonists and antagonists (2,3). some studies have ...

the immune responses that develop following epstien-barr virus (ebv) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. to evaluate the immune response, flow cytometric analysis of the peripheral blood of six patients during the acute phase of ebv infection was performed. this analysis revealed a significant increase in the percentages and th...