Tuberculosis is a serious opportunistic infection that may affect transplant recipients. The incidence of tuberculosis among such persons is 20-74 times higher than that for the general population, with a mortality rate of up to 30%. The most common form of acquisition of tuberculosis after transplantation is the reactivation of latent tuberculosis in patients with previous exposure. Clinical p...

We were greatly impressed by the Joint Tuberculosis Committee guidelines on the management of opportunist mycobacterial infections. We do, however, wonder why the word “opportunist” has been used to describe the mycobacteria, other than the M tuberculosis complex, that cause human disease. All mycobacteria causing disease, even the M tuberculosis complex, are opportunists. Thus, the latter are ...

Pelvic tuberculosis is a type of extrapulmonary tuberculosis. The disease is accompanied by clinical and laboratory findings which may be unspecific and present aspects of other diseases, including gynecological malignancies. In this report, the authors presented a case of pelvic tuberculosis associated with peritoneal tuberculosis in a young woman exhibiting imaging and tumor markers consisten...

In its typical form, spinal tuberculosis (TB) presents as destroyed contiguous vertebral bodies with involvement of intervertebral discs and paravertebral or psoas abscesses. Atypical forms are uncommonly reported. Here, we describe 8 patients with noncontiguous multisegmental spinal TB with no intervertebral disc involvement. From 2013 to 2014, we surgically treated 384 patients with spinal TB...

1 GeIb AF, Tashldn DP, Epstein JD, Szeftel A, Fairshter R. Physiologic characteristics of malignant unilateral main-stem bronchial obstruction. Am Rev Respir Dix 1988; 138:1362-85 2 Gelb AF, Epstein JD. Laser in treatment oflung cancer. Chest 1984; 86:662-66 3 Healy F, Wilson AF, Fairshter RD. Physiologic correlates of airwaycollapse in chronic airfiowobstruction. Chest 1984; 85:47681 4 Jayaman...

Heat shock proteins (Hsps) are a diverse set of proteins that mediate the correct folding, assembly, transport and degradation of other proteins. The Hsps have thus appropriately been termed as molecular chaperones. The 60kDa heat shock proteins (Hsp60s) form a sub-group of Hsps and are found to exist in all domains of life. In bacteria Hsp60s are encoded by the essential hsp60 genes arranged o...

Roxithromycin has recently been shown to possess significant in vitro activity against a variety of atypical mycobacteria such as the M. avium complex, M. scrofulaceum, M. szulgai, M. malmoense, M. xenopi, M. marinum, and M. kansasii and rare pathogens like M. chelonei and M. fortuitum. In the present investigation, screening of its in vitro activity was further extended by testing it against 3...

background since tuberculosis (tb) is a major public health problem that is a leading cause of mortality and morbidity among infectious diseases worldwide, early diagnosis and treatment are important to control an effective tuberculosis (tb) and also the increasing number of patients with atypical manifestations of active tb. it suggests more evaluation for active tb in fibrotic lesion in ct sc...

INTRODUCTION Because a substantial number of patients present with few or atypical symptoms, the recognition of tuberculosis remains challenging. Disseminated tuberculosis presenting with septic shock has already been described in some case reports, but, to the best of our knowledge, it has never been associated with polymorphonuclear effusion. CASE PRESENTATION We describe the case of a 27-y...

The nature and incidence of bacteriologically confirmed mycobacterial disease in south east England over the eight year period 1977-84 has been determined by a study of cultures received by the PHLS Regional Centre for Tuberculosis Bacteriology at Dulwich. The number of cases of tuberculosis in the ethnic European population has shown a decline, more so among males than females, but there has n...