introduction: one of the most common pathologies in neonates is hyperbilirubinemia, which is a good marker for damage to the central nervous system. the sensitivity of the auditory system to bilirubin has been previously documented, with much discrepancy in its effects on auditory brainstem response results. thus the objective of this study was to evaluate the effects of hyperbilirubinemia on a...

Low threshold Ca2+ currents mediated by T-type channels underlie burst spike activities of relay neurons in the thalamus. We have previously reported that knock-out mice for T-type channels show an enhanced nociceptive response to visceral pain, accompanied by an increase in tonic spikes in the absence of burst spikes in thalamic relay neurons. These results raised a possibility that T-type cha...

UNLABELLED The differential diagnosis of hearing loss with air and bone Auditory Brainstem Response in small children has not been enough studied in Brazil. AIM To compare air and bone Auditory Brainstem Response results in children under 2 months of age with normal hearing. STUDY DESIGN clinical with transversal cohort. MATERIALS AND METHODS 12 children who passed the hearing screening w...

When noise obstructs portions of target sounds the auditory system fills in missing information, a phenomenon known as auditory restoration or induction. Previous work in animal models demonstrates that neurons in primary auditory cortex (A1) are capable of restoring occluded target signals suggesting that early auditory cortex is capable of inducing continuity in discontinuous signals (i.e., e...

To our knowledge, the effects of Spirulina platensis water extract (SP) on hearing function have not yet been reported. This study investigated the effects of SP on the function and redox status of the auditory system. Auditory brainstem responses and redox status were compared between two groups of 3-month-old senescence-accelerated prone-8 (SAMP8) mice: the control group was fed a normal diet...

In two newborn infants who had experienced severe asphyxial insults, and who showed noticeable signs of brainstem dysfunction, all components of the auditory brainstem response except the eighth nerve potential became undetectable. Both babies survived, their brainstem responses returned, and one of them is judged to be developmentally normal at the age of 18 months. Clinical signs of brainstem...