Keratinocytes injured acutely by UVB light or lipopolysaccharide were used to test the hypothesis that keratinocyte injury promotes bacterial adherence and the development of group A streptococcal skin infections. Injury did not affect adherence to undifferentiated and differentiated keratinocytes, but keratinocyte differentiation promoted adherence four- to fivefold.

Epidermal naevi are a heterogenous group of benign congenital hamartomas that may be composed of cells of sebaceous, apocrine, eccrine, follicular, or keratinocyte origin. Verrucous epidermal naevi (VEN) are a type of epidermal naevi of keratinocyte differentiation.1 Although multiple lesions of VEN are often seen, lesions presenting bilaterally are rare. We present a case of VEN involving the ...

Double-hit lymphoma (DHL) has been identified as a subset of diffuse large B-cell lymphoma with poor clinical outcomes. It is because of genetic translocation of C-myc and Bcl2 gene that make it more aggressive and un-responsive to conventional and salvage treatments. DHLis an extremely rare entity of non-Hodgkin's lymphoma (NHL) having no established incidence data so far. In literature very l...

The rabbit anterior chamber was used for the implantation of specifically sensitized autologus lymph node tissue, and the response to local and systemic injection of antigen studied. Clinical observation of the sensitized eye following challenge with specific antigen showed a marked hemorrhagic iritis with typical anterior chamber "flare" and fbrinous exudate. This response occurred within hour...