نتایج جستجو برای: b cell activation factor

تعداد نتایج: 3081244  

Journal: :Annals of the Rheumatic Diseases 1990

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1995
T Kobata S Jacquot S Kozlowski K Agematsu S F Schlossman C Morimoto

CD27, a member of the tumor necrosis factor (TNF) receptor family, binds to its ligand CD70, a member of the TNF family, and subsequently induces T-cell costimulation and B-cell activation. CD27 is expressed on resting T and B cells, whereas CD70 is expressed on activated T and B cells. Utilizing transfected murine pre-B-cell lines expressing human CD27 or CD70, we have examined the effect of s...

Journal: :Proceedings of the National Academy of Sciences 1985

Background: Melanoma is a common and malignant cutaneous tumor, which is responsible for a large proportion of skin cancer deaths. Dendritic cell (DC)-based vaccines have achieved positive results in the treatment of melanoma because of their ability to induce cytotoxic response to facilitate tumor elimination. Objective: To improve the efficacy of dendritic ce...

ژورنال: پژوهش در پزشکی 2010
امامقلی پور1، , سلاله, بنده پور2، , مژگان, شعبانی1، , پریسا, کاظمی*, بهرام, سید2، , نگار , ماغن2، , لیلا , یغمایی1، , بهرام ,

Abstract Background: Factor VII, is a coagulant protease it begins the proteolytic cascade reactions and produces thrombin. The use of recombinant human factor VII, (rhFVII) is effective for the treatment of patients with hemophilia A or B. It is a target for gene therapy. This study was done to clone factor VII from HepG2 cell line. Methods: RNA was extracted from the hepatoma, (HepG2), ...

Journal: :Arthritis Research & Therapy 2009
Laurent Messer Ghada Alsaleh Jean-Marie Freyssinet Fatiha Zobairi Isabelle Leray Jacques-Eric Gottenberg Jean Sibilia Florence Toti-Orfanoudakis Dominique Wachsmann

INTRODUCTION In the present study, we investigated the ability of microparticles isolated from synovial fluids from patients with rheumatoid arthritis or osteoarthritis to induce the synthesis and release of key cytokines of B-lymphocyte modulation such as B cell-activating factor, thymic stroma lymphopoietin, and secretory leukocyte protease inhibitor by rheumatoid fibroblast-like synoviocytes...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه - دانشکده منابع طبیعی 1393

تحقیقات مختلف اثبات نموده اند که رشد و محتوای بیوشیمیایی روتیفرها می تواند تحت تاثیر نوع غذا و غلظت مواد غذایی تغییر نماید. ریز جلبک ها به عنوان یکی از منابع غذایی مهم برای کشت روتیفرها به ویژه از لحاظ شاخص های نظیر رشد، بقا، میزان پروتئین، چربی و اسیدهای چرب، ضروری می باشند. لذا تحقیق حاضر جهت مقایسه جلبک خشک (کلرلای پودری) و جلبک های تازه (ایزوکرایسیس گالبانا و نانوکلروپسیس آکولاتا) بر رشد، ت...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Rebecca A Sweet Michelle L Ols Jaime L Cullen Ashley Viehmann Milam Hideo Yagita Mark J Shlomchik

Extrafollicular (EF) B-cell responses are increasingly being recognized as an alternative pathway of B-cell activation, particularly in autoimmunity. Critical cellular interactions required for the EF B-cell response are unclear. A key question in autoimmunity, in which Toll-like receptor (TLR) signals are costimulatory and could be sufficient for B-cell activation, is whether T cells are requi...

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