In the rat barrel cortex, neurons in layer 4 are topographically arranged in a precise columnar structure, and the excitatory feed-forward input from layer 4 to layer 2/3 projects almost exclusively within the home barrel column. Here we analyzed the lateral connectivity that links neighboring columns in layer 2/3, which is necessary for integrating information across whiskers. We examined the ...

Chondroitin sulfate proteoglycans (CSPGs) consist of chondroitin sulfate (CS) glycosaminoglycans (GAGs) and core protein and regulate the migration, axonal outgrowth, and synaptogenesis in mammalian brains. In the present study, we investigated the localization of CSPGs, the effects of sensory deprivation on the density of perineuronal nets (PNNs), and the effects of chondroitinase ABC (Chase) ...

Sheth, Bhavin R., Christopher I. Moore, and Mriganka Sur. sponses might be the significant differences in response charTemporal modulation of spatial borders in rat barrel cortex. J. acteristics of the two thalamic nuclei ( the ventral posterior Neurophysiol . 79: 464–470, 1998. We examined the effects of medial (VPm) nucleus and the posterior medial (POm) nuvarying vibrissa stimulation frequen...

The effects of "barrel cortex" ablation upon the biometrics of "exploratory" whisking were examined in three head-fixed rats which had previously sustained unilateral ablation of the left cortical "barrel field" under electrophysiological control. Unconditioned movements of a pair of bilaterally homologous whiskers (C-1, Right, Left) were monitored, optoelectronically, with other whiskers prese...

layer 2/3 of mouse barrel cortex Microcircuits of excitatory and inhibitory neurons in You might find this additional info useful...

layer 2/3 of mouse barrel cortex Microcircuits of excitatory and inhibitory neurons in You might find this additional info useful...

The recurrent synaptic architecture of neocortex allows for self-generated network activity. One form of such activity is the Up state, in which neurons transiently receive barrages of excitatory and inhibitory synaptic inputs that depolarize many neurons to spike threshold before returning to a relatively quiescent Down state. The extent to which different cell types participate in Up states i...