Already in the early stages of Case-Based Reasoning prototypes were considered as an interesting technique to structure the case base and to fill the knowledge gap between single cases and general knowledge. Unfortunately, later on prototypes never became a hot topic within the CBR community. However, for medical applications they have been used rather regularly, because they correspond to the ...

It is a constant challenge for teachers to keep up with the ever-changing technological advances in the world today. Current teachers often struggle with how to use technology to enhance their students’ learning experiences. Teacher education programs have a responsibility to offer both pre-service and in-service teachers strategies and methods for effectively using technology in their teaching...

In many contexts, exclusive breastfeeding combined with antiretroviral treatment ensures the best chance of HIV-free survival of infants exposed to HIV. Counseling, peer support, education and community awareness can increase uptake of exclusive breastfeeding. This document is part of a series of briefs for health program managers interested in implementing evidence-based programs. With a speci...

We present a new computational method for solving a classical problem, the identification problem of cis-regulatory motifs in a given set of promoter sequences, based on one key new idea. Instead of scoring candidate motifs individually like in all the existing motif-finding programs, our method scores groups of candidate motifs with similar sequences, called motif closures, using a P-value, wh...

Poverty is a complex issue that is rarely conducive to analysis in laboratory or field experiments. Effective interventions that aim to decrease or eliminate poverty require an understanding of the intricate web of associated social issues. The need for this increased comprehension necessitates the use of alternative robust means of analysis: one such being agent-based modelling. The strengths ...

background: we aimed to assess the impact of health workers’ training program on preventive behaviors of leishmaniosis based on basnef (belief, attitude, subjective norm, and enabling factors) model in the families under the coverage of health centers. methods: the study was done in rural health centers of marvdasht city, fars province, iran in 2011. health workers completed a specific question...

background and purpose: studies have shown the advantages of e-cme programs. developing case-based e-cme activities, one of the popular formats of e-cme programs, is difficult and time consuming. in this article we describe our experience of performing instructional system design for creating case-based e-cme contents.  methods: we performed a five-step instructional system design (i.e. system ...