نتایج جستجو برای: basophil activation test
تعداد نتایج: 1222054 فیلتر نتایج به سال:
Lymphocyte transformation test (LTT) is a widely used assay to detect drug-specific T cell reaction, but its relatively low sensitivity renders risk for pseudo-negativity. Basophil activation test (BAT) is an emerging assay initially used to diagnose food allergy, but its application to drug hypersensitivity as been reported anecdotally. Although a promising assay, the clinical settings or a pa...
BACKGROUND Colonization by Aspergillus fumigatus in patients with cystic fibrosis (CF) can cause A fumigatus sensitization and/or allergic bronchopulmonary aspergillosis (ABPA), which affects pulmonary function and clinical outcomes. Recent studies show that specific allergens upregulate the surface-expressed basophil marker CD203c in sensitized subjects, a response that can be readily measured...
BACKGROUND For most physicians, quantification of drug-specific immunoglobulin E (drug-sIgE) antibodies constitutes the primary in vitro measure to document immediate drug hypersensitivity reactions (IDHR). Unfortunately, this is often insufficient to correctly identify patients with IgE-mediated IDHR and impossible for non-IgE-mediated IDHR that result from alternative routes of basophil and m...
P4: REAL WORLD PERFORMANCE OF BASOPHIL ACTIVATION TEST IN PEANUT ALLERGY: A SINGLE CENTRE EXPERIENCE
human basophils play a key role in allergic diseases such as asthma and in a variety of immunological disorders. the generation of il-4 and il-13 can be induced from basophil by ige-mediated and non-ige-mediated mechanisms. time and stimulus- dependent differences in the regulation of these cytokines could have relevance to their biological effects. the aim o...
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