نتایج جستجو برای: bedaquiline

تعداد نتایج: 462  

Journal: : 2023

The objective : to evaluate the efficacy and safety of bedaquiline in new chemotherapy regimens HIV-positive tuberculosis patients. Subjects Methods . Treatment results 60 patients with TB/HIV co-infection using treatment containing were analyzed. Results. Patients demonstrated poor adherence treatment, so 46/60 (76.6%) did not complete intensive phase chemotherapy. use cause a critical prolong...

Journal: :Antimicrobial agents and chemotherapy 2012
Kathy Williams Austin Minkowski Opokua Amoabeng Charles A Peloquin Dinesh Taylor Koen Andries Robert S Wallis Khisimuzi E Mdluli Eric L Nuermberger

Novel oral regimens composed of new drugs with potent activity against Mycobacterium tuberculosis and no cross-resistance with existing agents are needed to shorten and simplify treatment for both drug-susceptible and drug-resistant tuberculosis. As part of a continuing effort to evaluate novel drug combinations for treatment-shortening potential in a murine model, we performed two long-term, r...

Journal: :Journal of Pharmacology and Pharmacotherapeutics 2014

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