نتایج جستجو برای: benzo
تعداد نتایج: 7873 فیلتر نتایج به سال:
Synthesis, Characterization and Biological Activity of Various Substituted Benzothiazole Derivatives
A series of 2-(benzo[d]thiazol-2-ylthio)-N-(2-oxoindolin-3-ylidene)acetohydrazide (3a3g), 2-(benzo [d]thiazol-2-ylthio)-N-(2,4’-dioxospiro[indolin-3,2’-thiazolidin)-3’yl)acetamide (4a-4g) and 2'-((benzo[d]thiazol-2-ylthio)methyl)spiro[indoline-3,5'thiazolo[4,3-b][1,3,4]oxadiazol]-2-ones (5a-5g) have been synthesized and screened for their anti-inflammatory, analgesic and antibacterial activitie...
serstoff waren, je 0,1 /ug an Benzo(e)pyren, Benzo(a)pyren, Perylen, Anthanthren, Benzo(ghi)perylen, Dibenz(a,h) anthracen und Coronen zugesetzt und alle Komponenten mit der beschriebenen Me thode wiedergefunden. Noch wesentlich empfind licher sind die betrachteten Kohlenwasserstoffe durch eine anschließende Dünnschichtchromatographie (Fertigplatten Merck A120 3 Typ E, Cyclohexan-isoOetanol-X...
The cell transforming ability of asbestos dusts was investigated using C3H10T1/2 murine fibroblasts. In a series of experiments, crocidolite and amosite caused no increase in the number of transformed colonies over that seen in cultures from untreated cells. The dusts were, however, capable of augmenting the oncogenic effect of benzo(a)pyrene. This synergistic effect was evident when fibers and...
serstoff waren, je 0,1 /ug an Benzo(e)pyren, Benzo(a)pyren, Perylen, Anthanthren, Benzo(ghi)perylen, Dibenz(a,h) anthracen und Coronen zugesetzt und alle Komponenten mit der beschriebenen Me thode wiedergefunden. Noch wesentlich empfind licher sind die betrachteten Kohlenwasserstoffe durch eine anschließende Dünnschichtchromatographie (Fertigplatten Merck A120 3 Typ E, Cyclohexan-isoOetanol-X...
Syrian golden hamsters were placed on a control or vitamin A-deficient diet. When their serum vitamin A content was significantly reduced, i.e., to less than 10% of controls, the hamsters were killed and lung aryl hydrocarbon hydroxylase activity and metabolism of benzo(a)pyrene were determined. The benzo(a)pyrene metabolite profile was similar with control and A-deficient systems, and only few...
Seven phenols of benzo(a)pyrene (4-, 5-, 6-, 7-, 8-, 9-, and 10-hydroxybenzo(a)pyrene) were tested for carcinogenicity on mouse skin by application of 0.4 mumole of compound once every two weeks for 56 weeks. None of the seven phenols tested was carcinogenic to mouse skin, while treatment with the same dose of benzo(a)pyrene produced tumors in 92% of the treated animals. The lack of carcinogeni...
The title compound, C(26)H(18)Cl(2)O, is a heterocyclic structure consisting of a benzo[f]chromene ring and two aromatic rings. The non-H atoms of the benzo[f]chromene ring are almost coplanar (rms deviation = 0.107 Å), and the methyl C atom lies 1.340 (4) Å from the mean plane of the benzo[f]chromene ring. The chromene ring forms dihedral angles of 88.45 (2)° with the benzene ring linked to th...
A Pd(II)-catalyzed Sonogashira type cross-coupling reaction between 2-iodothiophenol and phenylacetylene has been developed. A series of 2-substituted benzo[b]thiophenes were obtained in moderate to good yield (up to 87%). The application of this method was demonstrated by the synthesis of 2-(4-(tert-butyl)phenyl)benzo[b]thiophene 1,1-dioxide and (4-methoxyphenyl)(2-(4-methoxyphenyl) benzo[b]th...
a fast and simple modified quechers extraction method was developed for determination of benzo[a]pyrene (bap) in 137 traditional (sangak), semi-industrial (sangak) and industrial bread samples using spiked calibration curves by gc/ms. sample preparation includes extraction of bap into acetone followed by cleanup with dispersive solid phase extraction. the limit of detection and limit of quantif...
The metabolism of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene results primarily in the ultimate carcinogenic metabolite of benzo[a]pyrene, 7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene and to a lesser extent 7,8-dihydroxy-9,10-dioxetane-7,8,9,10-tetrahydrobenzo[a]pyrene, from which chemiluminescence is observed. This specific microsomal chemiluminescence has been used to establish that t...
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