and processes, from the storage and reproduction of genetic information to the control of developmental processes to the sophisticated computations performed by the nervous system. Much as human technology uses electronic microprocessors to control electromechanical devices, biological organisms use biochemical circuits to control molecular and chemical events. The engineering and programming o...

Structure-guided active-site redesign of a family GT-80 β-D-galactoside sialyltransferase (from Pasteurella dagmatis) to change enzyme regioselectivity from α-2,3 in the wild type to α-2,6 in a P7H-M117A double mutant is reported. Biochemical data for sialylation of lactose together with protein crystal structures demonstrate highly precise enzyme engineering.

1 Department of Evolutionary Ecology, Do~nana Biological Station—CSIC, Sevilla, Spain 2 National Museum of Natural Sciences—CSIC, Madrid, Spain 3 Department of Molecular Biology and Biochemical Engineering, Pablo de Olavide University, Sevilla, Spain 4 Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan Correspondence Ismael Galv!an, e-mail: galvan...

Volume 3 • Issue 3 • 1000139 J Bioproces Biotechniq ISSN:2155-9821 JBPBT, an open access journal *Corresponding author: Jaqueline do Nascimento, Department of Biochemical Engineering, School of Chemistry, Federal University of Rio de Janeiro, Cidade Universitária, Centro de Tecnologia, Bl. E, Sl. 203, Ilha do Fundão, 21941-909, Rio de Janeiro, Brasil, Tel: 55-21-2562-7568; Fax: 5521-2562-7567; ...

1 Unit of Physiology, University of Jaén, 23071 Jaén, Spain 2Department of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL 33328-2018, USA 3 Center of Biomedical Engineering, University Camilo Castelo Branco, 12247-004 São José dos Campos, SP, Brazil 4Department of Molecular and Biochemical Pharmacology, Vrije Universiteit Brussel, 1050 Brussels, ...

Recent advances in surface engineering and soft lithography provide tools to fabricate patterned surfaces and microfluidic devices with dimensions comparable to the sizes of single mammalian cells. These technologies enable the studies of individual cells on spatially well-defined, patterned surfaces, and in contact with patterned liquid media. They provide information about cells impossible to...

Tijana Đorđević1*, Slavica Šiler-Marinković2, Rada Đurović-Pejčev1, Suzana Dimitrijević-Branković2 and Jelena Gajić Umiljendić1 1Institute of Pesticides and Environmental Protection, 11080 Belgrade, Serbia ([email protected]) 2University of Belgrade, Faculty of Technology and Metallurgy, Division of Biochemical Engineering and Biotechnology, Karnegijeva 4, 11000 Belgrade, Serbia Rec...

This paper focuses on polynomial dynamical systems over finite fields. These systems appear in a variety of contexts, in computer science, engineering, and computational biology, for instance as models of intracellular biochemical networks. It is shown that several problems relating to their structure and dynamics, as well as control theory, can be formulated and solved in the language of algeb...

1 Rearch Institute, Mitsui Knowledge Industry Co., Ltd, 2-7-14 Higashinakano, Nakanoku, Tokyo 164-8555, Japan 2 Department of Biochemical Engineering and Science, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka, Fukuoka 820-8502, Japan 3 Laboratory for Applied Biological Regulation Technology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1, Hakozaki...