In honoring Tom Merigan, I present details of studies from our laboratory on the virus–dendritic cell (DC) interaction that leads to immunosuppression, and I dwell at some length on the initiating mechanism of this interaction, the release of type I interferon (IFN) in DCs. In this prologue, I reminisce about some of my long-time interactions with Tom. Interestingly, it was nearly 30 years ago ...
