نتایج جستجو برای: birc5

تعداد نتایج: 294  

Journal: :Galen Medical Journal 2022

Background: Diagnosis and treatment of multiple sclerosis (MS) in its advanced state have been one the medical community's concerns so far. Cell therapy has a modern successful treatment. However, it not yet effective enough to treat MS. This study aimed find relationship between neural stem cells (NSCs) MS, by considering important signaling pathways pathogenesis, most microRNAs (miRNAs) for d...

2015
Matthias Kolberg Maren Høland Guro E. Lind Trude H. Ågesen Rolf I. Skotheim Kirsten Sundby Hall Nils Mandahl Sigbjørn Smeland Fredrik Mertens Ben Davidson Ragnhild A. Lothe

No consensus treatment regime exists beyond surgery for malignant peripheral nerve sheath tumours (MPNST), and the purpose of the present study was to find new approaches to stratify patients with good and poor prognosis and to better guide therapeutic intervention for this aggressive soft tissue cancer. From a total of 67 MPNSTs from Scandinavian patients with and without neurofibromatosis typ...

Journal: :Clinical chemistry 2006
Paul N Span Vivianne C G Tjan-Heijnen Joop J T M Heuvel Jacques B de Kok John A Foekens Fred C G J Sweep

BACKGROUND A total of 4 additional splice variants (survivin-DeltaEx3, survivin 2alpha, survivin-2B, and survivin-3B) have been described for survivin [baculoviral IAP repeat-containing protein (BIRC-5), approved gene symbol BIRC5], which has been implicated in both inhibition of apoptosis and regulation in mitosis in many tumor types. In this study, we assessed whether the survivin splice vari...

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