نتایج جستجو برای: bird helminth

تعداد نتایج: 28941  

2015
Johannes Charlier Valérie De Waele Els Ducheyne Mariska van der Voort Fiona Vande Velde Edwin Claerebout

Helminth infections of cattle affect productivity in all classes of stock, and are amongst the most important production-limiting diseases of grazing ruminants. Over the last decade, there has been a shift in focus in the diagnosis of these infections from merely detecting presence/absence of infection towards detecting its impact on production. This has been facilitated by studies observing co...

Journal: :Immunology 2009
Joseph A Jackson Ida M Friberg Susan Little Janette E Bradley

Although the molecules and cells involved in triggering immune responses against parasitic worms (helminths) remain enigmatic, research has continued to implicate expansions of T-helper type 2 (Th2) cells and regulatory T-helper (T(reg)) cells as a characteristic response to these organisms. An intimate association has also emerged between Th2 responses and wound-healing functions. As helminth ...

Journal: :The Journal of clinical investigation 2015
Leticia Monin Kristin L Griffiths Wing Y Lam Radha Gopal Dongwan D Kang Mushtaq Ahmed Anuradha Rajamanickam Alfredo Cruz-Lagunas Joaquín Zúñiga Subash Babu Jay K Kolls Makedonka Mitreva Bruce A Rosa Rosalio Ramos-Payan Thomas E Morrison Peter J Murray Javier Rangel-Moreno Edward J Pearce Shabaana A Khader

Parasitic helminth worms, such as Schistosoma mansoni, are endemic in regions with a high prevalence of tuberculosis (TB) among the population. Human studies suggest that helminth coinfections contribute to increased TB susceptibility and increased rates of TB reactivation. Prevailing models suggest that T helper type 2 (Th2) responses induced by helminth infection impair Th1 immune responses a...

2017
Naomi Aira Anna-Maria Andersson Susmita K Singh Derek M McKay Robert Blomgran

BACKGROUND In countries with a high prevalence of tuberculosis there is high coincident of helminth infections that might worsen disease outcome. While Mycobacterium tuberculosis (Mtb) gives rise to a pro-inflammatory Th1 response, a Th2 response is typical of helminth infections. A strong Th2 response has been associated with decreased protection against tuberculosis. PRINCIPAL FINDINGS We i...

Journal: :Journal of immunology 2008
David E Elliott Ahmed Metwali John Leung Tommy Setiawan Arthur M Blum M Nedim Ince Lindsey E Bazzone Miguel J Stadecker Joseph F Urban Joel V Weinstock

Helminth exposure appears to protect hosts from inappropriate inflammatory responses, such as those causing inflammatory bowel disease. A recently identified, strongly proinflammatory limb of the immune response is characterized by T cell IL-17 production. Many autoimmune type inflammatory diseases are associated with IL-17 release. Because helminths protect from these diseases, we examined IL-...

2017
Ruud H. P. Wilbers Lotte B. Westerhof Kim van Noort Katja Obieglo Nicole N. Driessen Bart Everts Sonja I. Gringhuis Gabriele Schramm Aska Goverse Geert Smant Jaap Bakker Hermelijn H. Smits Maria Yazdanbakhsh Arjen Schots Cornelis H. Hokke

Helminth parasites control host-immune responses by secreting immunomodulatory glycoproteins. Clinical trials and mouse model studies have demonstrated the potential of helminth-derived glycoproteins for the treatment of immune-related diseases, like allergies and autoimmune diseases. Studies are however hampered by the limited availability of native parasite-derived proteins. Moreover, recombi...

Journal: :Folia parasitologica 2001
J G Esteban B Amengual J S Cobo

The community composition and structure of helminths of Pipistrellus pipistrellus (Schreber, 1774) from two widely separated Spanish localities, El Saler (n = 42) and the San Pedro pothole (n = 34), were determined and compared. Five species of trematodes, Plagiorchis (Plagiorchis) sp., Lecithodendrium (Lecithodendrium) linstowi Dollfus, 1931, Prosthodendrium (Prosthodendrium) sp., Pycnoporus h...

2010
Hermelijn H. Smits Bart Everts Franca C. Hartgers Maria Yazdanbakhsh

Developed countries are suffering from an epidemic rise in immunologic disorders, such as allergy-related diseases and certain autoimmunities. Several studies have demonstrated a negative association between helminth infections and inflammatory diseases (eg, allergy), providing a strong case for the involvement of helminth infections in this respect. However, some studies point in the opposite ...

2013
Stephen A Redpath Nienke van der Werf Ana M Cervera Andrew S MacDonald David Gray Rick M Maizels Matthew D Taylor

Foxp3(+) regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity. Little is yet known regarding the co-stimulatory environment that favours the development of Foxp3(+) Treg-cell responses during helminth infe...

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