In 1987, the United States Department of Agriculture (USDA-ARS) National Sedimentation Laboratory, in cooper­ ation with the Mississippi Agricultural and Forestry Experi­ ment Station (MAFES) and the Natural Resources Conservation Service (NRCS), initiated an interdisciplinary research project to develop profitable and environmentally sustainable conservation production systems for silty upland...

Bitter taste perception is innate and induces aversive reactions. Since numerous harmful compounds, including secondary plant metabolites, synthetic chemicals, inorganic ions and rancid fats, do taste bitter, this basic taste modality may be considered as a defence mechanism against the ingestion of potential poisons. For a complete understanding of this defence mechanism it is obligatory to id...

Mammals can taste a wide repertoire of chemosensory stimuli. Two unrelated families of receptors (T1Rs and T2Rs) mediate responses to sweet, amino acids, and bitter compounds. Here, we demonstrate that knockouts of TRPM5, a taste TRP ion channel, or PLCbeta2, a phospholipase C selectively expressed in taste tissue, abolish sweet, amino acid, and bitter taste reception, but do not impact sour or...

A phylogenetic-like tree of structural fragments has been constructed to extract useful insights from a structural database of bitter molecules. The tree of structural fragments summarizes the substructural groups present in the molecules from the bitter database. These structural fragments are compared with a large number of random molecules to highlight substructures specific to bitter molecu...

in order to evaluate quantity and quality hairy vetch (vicia villosa l.) yield in the pure and mixed cropping with barley (hordeum vulgare l.) and triticale (triticosecale) the experiment was conducted at agricultural research station (khodabande) under dryland conditions during 2006 -2008. field experiments were arranged in a randomized complete blocks design with 9 treatments in four replicat...

Background & aim: The fruit of Citrullus colocynthis has a bitter taste and antibacterial properties against pathogen factors.The aim of current research was to study the effects of different dietary level of bitter cucumber fruit powderwith and without protexin probiotic supplementation on growth performance, carcass traits and intestinal morphology of broiler chicks....

Many (dietary) bitter compounds, e.g. flavonoids, activate bitter receptor hTAS2R39 in cell-based assays. Several flavonoids, amongst which some flavanones, are known not to activate this receptor. As certain flavanones are known to mask bitter taste sensorially, flavanones might act as bitter receptor antagonists. Fourteen flavanones were investigated for their potential to reduce activation o...

Earlier, a family of G protein-coupled receptors, termed T2Rs, was identified in the rodent and human genomes through data mining. It was suggested that these receptors mediate bitter taste perception. Analysis of the human genome revealed that the hT2R family is composed of 25 members. However, bitter ligands have been identified for only three human receptors so far. Here we report identifica...

The aim of this study was to determine if taste interactions occur when bitter stimuli are mixed. Eight bitter stimuli were employed: denatonium benzoate (DB), quinine-HCl (QHCl), sucrose octaacetate (SOA), urea, L-tryptophan (L-trp), L-phenylalanine (L-phe), ranitidine-HCl, and Tetralone. The first experiment constructed individual psychophysical curves for each subject (n = 19) for each compo...