background: recombinant activated factor vii induces hemostasis in patients with coagulopathy disorders. aryoseven™ as a safe iranian recombinant activated factor vii has been available on our market. this study was performed to establish the safety of aryoseven on patients with coagulopathy disorder. methods: this single-center, descriptive, cross sectional study was carried out in thrombus an...

BACKGROUND We studied (1) the rates of stroke or systemic embolism and bleeding in patients with atrial fibrillation and peripheral artery disease (PAD) and (2) the efficacy and safety of apixaban versus warfarin in patients with atrial fibrillation with and without PAD. METHODS AND RESULTS The Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE)...

Vol. 33 No. 1 • January 2008 • P&T® 51 a combination of death from cardiovascular disease, MI, and stroke. Safety endpoints were TIMI major bleeding episodes and life-threatening bleeding. The clopidogrel group reached the primary endpoint more frequently (12.1% of the time) than the prasugrel group (9.3%); the hazard ratio (HR) was 0.81 (P = 0.004). The benefit was significant in both loading ...

OBJECTIVE To determine the efficacy and safety of enoxaparin compared with unfractionated heparin during percutaneous coronary intervention. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline and Cochrane database of systematic reviews, January 1996 to May 2011. STUDY SELECTION Randomised and non-randomised studies comparing enoxaparin with unfractionated heparin during perc...

BACKGROUND Although the reduction in mortality with bivalirudin compared with unfractionated heparin plus glycoprotein IIb/IIIa inhibitors in the Harmonizing Outcome with Revascularization and Stent in Acute Myocardial Infarction (HORIZONS-AMI) trial has been attributed to lower rates of major bleeding, alternative mechanisms have not been investigated in depth. We sought to investigate whether...

â  a 56 year-old man with recurrent gastrointestinal bleeding is reported. the patient had constant crampy pain in his epigastrium, right upper quadrant and periumbilical area. upper-gastrointestinal endoscopy was normal. colonoscopy showed a soft-tissue mucoâ­sal lesion in the rectum which was determined to be a worm that extended into the lumen of the rectum with no bleeding. the pathology wa...

conclusion superselective tae for lgi bleeding has a high success and low complication rate. there are no statistical correlations between the clinical success rate and several variables, including embolic material, embolization site, and anticoagulant or antiplatelet medication. patients and methods fifty-two patients who underwent superselective tae for lgi bleeding between 2003 and 2011 were...

[no abstract available]

abstract today, the laser is used in a wide range of dental procedures. some of the advantages of some lasers in treatment of oral soft tissue lesions are: elimination of need for local anesthesia, minimal bleeding, fast healing, absence of postoperative complications and reduction of recurrence rate. for these reasons is was used for treatment of oral fibroma. to our knowledge this is the firs...

In a recent study, investigators of the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE A) enrolled 7554 patients with atrial fibrillation (AF) at high risk of developing vascular events such as stroke, myocardial infarction, systemic embolism, and vascular death.1 These patients, in whom anticoagulation was contraindicated, were randomly assigned...