mean value, but also 24h blood pressure variability seems to be independently related to the end organ damage of hypertension. This is illustrated in figure 1, which is taken from a study where 108 hypertensive patients underwent a 24h intra-arterial blood pressure monitoring in ambulatory conditions by Oxford technique 16. A score based on clinical and laboratory examinations was used to quant...

To investigate the association between cardiovascular mortality and short-term variabilities in blood pressure and heart rate, we performed a long-term prospective study of ambulatory blood pressure monitoring in Ohasama, Japan, starting in 1987. We obtained ambulatory blood pressure and heart rate in 1542 subjects >/=40 years of age. Blood pressure and heart rate variabilities were estimated a...

AIMS/INTRODUCTION Recent studies have shown the association between blood pressure variability and cardiovascular events. The present study was designed to investigate the relationship between antihypertensive drug class and home blood pressure variability in patients with type 2 diabetes. MATERIALS AND METHODS We compared home blood pressure variability among patients treated with calcium ch...

In addition to mean blood pressure, blood pressure variability is hypothesized to have important prognostic value in evaluating cardiovascular risk. We aimed to assess the prognostic value of blood pressure variability within 24 hours. Using MEDLINE, EMBASE and Cochrane Library to April 2013, we conducted a systematic review of prospective studies of adults, with at least one year follow-up and...

OBJECTIVE  To systematically review studies quantifying the associations of long term (clinic), mid-term (home), and short term (ambulatory) variability in blood pressure, independent of mean blood pressure, with cardiovascular disease events and mortality. DATA SOURCES  Medline, Embase, Cinahl, and Web of Science, searched to 15 February 2016 for full text articles in English. ELIGIBILITY ...

Patients with hypertension have a blunted sensitivity of baroreflex control of heart period. In these patients, baroreflex sensitivity is positively related to heart rate variability and inversely related to blood pressure variability. We hypothesized that this relationship would also be evident in healthy normotensive subjects and that individuals with higher baroreflex sensitivity would have ...

Blood pressure variability is the result of a complex interaction between external stimulation and several cardiovascular control mechanisms and is enhanced in all those conditions characterized by an impaired autonomic regulation of circulation. In particular, blood pressure variability is enhanced in hypertension over 24 h and may independently contribute to the cardiovascular complications o...

BACKGROUND AND PURPOSE In patients with acute ischemic stroke, a high blood pressure or a highly variable blood pressure is a common reason for withholding thrombolytic treatment, but guidelines recommend a conservative approach to active blood pressure lowering in this setting. We have performed exploratory analyses to study the clinical effects of blood pressure and early blood pressure-lower...