Polycrystalline copper electrocatalysts have been experimentally shown to be capable of reducing CO2 into CH4 and C2H4 with relatively high selectivity, and a mechanism has recently been proposed for this reduction on the fcc(211) surface of copper, which was assumed to be the most active facet. In the current work, we use computational methods to explore the effects of the nanostructure of the...

MiR-204 and miR-211 (miR-204/211) share the same seed site sequence, targeting many of the same genes. Their role in cancer development remains controversial, as both cell proliferative and suppressive effects have been identified. This study aimed to address the relationship between the two structurally similar microRNAs (miRs) by examining their target genes in depth as well as to reveal thei...

Avril Drummond1† & Lynn Legg2 †Author for correspondence 1Division of Rehabilitation and Ageing, B Floor, Medical School, Queens Medical Centre, Nottingham NG7 2UH, UK Tel.: +44 115 823 0226 Fax: +44 115 823 0231 Avril.Drummond@ nottingham.ac.uk 2Academic Section of Geriatric Medicine, Level 3, Centre Block, Royal Infirmary, Glasgow, UK Tel.: +44 141 211 4953 Fax: +44 141 211 4944 E-mail: step@...

Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of complicated bacteremia (CB) and infective endocarditis (IE). The gold standard treatment for these infections is vancomycin. A vancomycin area under the concentration-time curve from 0 to 24 h (AUC(24))/MIC ratio of >400 has been suggested as a target to achieve clinical effectiveness, and yet to date no study has quantitat...

BACKGROUND Prader-Willi syndrome (PWS) is often related to severe obesity and type-2 diabetes mellitus (T2DM). However, few studies, and none in Korea, have examined prevalence of T2DM and other variables in PWS. The aim of this study was to identify the prevalence and associated risk factors for T2DM in Korean patients with PWS. METHODS We performed a retrospective cohort study of the 84 PWS...