Insulin resistance (IR), an impaired cellular, tissue and whole body response to insulin, is a major pathophysiological defect of type 2 diabetes mellitus. Although IR is closely associated with obesity, the identity of the molecular defect(s) underlying obesity-induced IR in skeletal muscle remains controversial; reduced post-receptor signalling of the insulin receptor substrate 1 (IRS1) adapt...

High-density genetic linkage maps were constructed for the Japanese flounder (Paralichthys olivaceus). A total of 1624 microsatellite markers were polymorphic in the reference family. Linkage analysis using JoinMap 4.0 resulted in the mapping of 1487 markers to 24 linkage groups, a result which was consistent with the 24 chromosomes seen in chromosome spreads. The female map was composed of 125...

BACKGROUND Prophylactic use of low molecular weight heparin (LMWH) has been shown to be efficacious in decreasing thromboembolism. LMWHs are associated with increased rates of bleeding. OBJECTIVE We reviewed perioperative blood pressure dynamics for patients who experienced hematomas while undergoing body contouring procedures while receiving enoxaparin (Lovenox), compared with similar patien...

Figure 2. MRE Results. a) Magnitude image of the porcine globe imbedded in a bovine-gelatin substrate. b) Up-down sensitized wave image, showing the mode-conversion of 10-Hz longitudinal waves at the corneoscleral surface and propagation of the resulting shear waves inside the vitreous body. c) Shear stiffness map generated with a local frequency estimation algorithm, yielding an average stiffn...

We define the notion of critical points at infinity for charged N-body problem, following approach Albouy (1993). give a characterisation such and show how they can be found in 3-body problem. The symmetry group problem accompanying integrals play key role. In fact are indispensible understanding bifurcations integral map. Together with we present bifurcation values.

Modern radiation therapy (RT) treatment planning is based on multimodality imaging. With the recent availability of whole-body PET/MR hybrid imaging new opportunities arise to improve target volume delineation in RT treatment planning. This, however, requires dedicated RT equipment for reproducible patient positioning on the PET/MR system, which has to be compatible with MR and PET imaging. A p...

Xenopus embryos have been selected in which the second cleavage is occurring in a frontal plane, i.e. one tending to lie at right angles to the prospective plane of bilateral symmetry for the body pattern. Some of these have been used to deduce a map of the disposition of materials for the normal mesodermal pattern (the normal 'fate map') by injecting blastomeres to found fluorescently marked c...

Orthostatic tolerance is reduced in the heat-stressed human. This study tested the following hypotheses: 1) whole body heat stress reduces cerebral blood velocity (CBV) and increases cerebral vascular resistance (CVR); and 2) reductions in CBV and increases in CVR in response to an orthostatic challenge will be greater while subjects are heat stressed. Fifteen subjects were instrumented for mea...

Rotation intertwining maps from the set of convex bodies in R into itself that are continuous linear operators with respect to Minkowski and Blaschke addition are investigated. The main focus is on Blaschke-Minkowski homomorphisms. We show that such maps are represented by a spherical convolution operator. An application of this representation is a complete classification of all even BlaschkeMi...