AIM To evaluate reticulocyte hemoglobin (RET-He) vis-a-vis serum ferritin as a marker of bone marrow iron store in iron deficiency anemia (IDA). MATERIAL AND METHODS A hospital based analytic study was conducted among patients (age group 15-65 years) with newly diagnosed and untreated IDA admitted in medicine ward and not suffering from any inflammatory disorders (excluded by C-reactive prote...

Let G be a minimal imperfect P 5-free graph (i.e. a minimal imperfect graph not containing a path on 5 vertices as induced subgraph) and let S be a minimal cutset of G. In this paper we study several properties of such cutsets, in particular we prove that the subgraph induced by S is connected, contains a P 4 , cannot induce a bipartite subgraph of G .... As a by-product we also give a structur...

OBJECTIVE To investigate the performance of first-trimester screening for aneuploidies by including assessment of the fetal nasal bone in the combined test of maternal age, fetal nuchal translucency (NT) thickness, fetal heart rate (FHR) and serum free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A). METHODS Screening by the combined test was pe...

BACKGROUND There is significant heterogeneity in survival of patients with metastatic breast cancer who have bone-only metastasis. We studied the correlation of serum N-telopeptide (NTx), a marker of bone resorption, and its correlation with clinical outcomes in patients with metastatic breast cancer with bone-only or bone plus soft tissue metastasis. PATIENTS AND METHODS Serum was taken from...

Tooth eruption is an orientating action which migrates teeth coronally during life, even in bone or after occlusion contact is lost. The eruption pathway is due to bone resorption near the enamel crown and bone deposition around the cementum-covered roots. Due to their proximity to bone resorption and deposition, we hypothesize that the hard tissues enamel, dentine or cementum are important dur...

A tubular braided composite bone cast for improving the efficiency and quality of bone fracture treatment is investigated. Finite element analysis was used to evaluate stress concentrations in fracture sites supported with plate and tubular casts. The stress in a plated bone is 768 % of that in a whole bone at the same location, while it is only 47 % in a bone with a tubular cast. Three unbroke...

The importance of the bone microenvironment to the pathophysiology and morbidity associated with prostate cancer bone metastasis is becoming increasingly apparent. Significant alterations take place in the microenvironment of bone, which disturb the normal coupling that exists between bone resorption and bone formation. Consequently, a better understanding of the mechanisms that interact at the...

We present the case of a 16-year-old boy admitted with a large mediastinal mass. Both in the mediastinal tru-cut biopsy and the bone marrow biopsy, a malignant small round cell tumor was determined. The clinical diagnosis was leukemia or lymphoma. The cytoplasmic CD20 expression was shown on the tumor cells of the mediastinal tru-cut biopsy. Rhabdomyosarcoma was diagnosed by the...

This article puts the case for a new and evolving research approach or orientation „facet methodology‟, developed in collaborative team based working at Realities at the Morgan Centre, a „Node‟ of the UK National Centre for Research Methods. Research fields are seen as constructed through combinations and constellations of facets as we might see in a cut gemstone, where facets refract and inten...

Thyroid hormone (TH) is essential for bone development. Altered TH levels such as hyperthyroidism, or thyrotoxicosis, results in the early maturation of cartilaginous scaffold long development, which can cause improper ossification. Maternal hyperthyroidism during embryonic development causes neonatal thyrotoxicosis and therefore lead to stunted growth infants. In our avian model induced we inj...