Piezoelectric materials are the group of smart materials which have been recently developed for biomedical applications, such as bone tissue engineering. These materials could provide electrical signals with no external source power making them effective for bone remodeling. Between various types of materials, BaTiO3 and CaTiO3 are nontoxic piezoelectric ceramics, which recently have been intro...

The matrix metalloproteinase (MMP) family of extracellular proteases performs crucial roles in development and repair of the skeleton owing to their ability to remodel the extracellular matrix (ECM) and release bioactive molecules. Most MMP-null skeletal phenotypes that have been previously described are mild, thus permitting the assessment of their functions during bone repair in the adult. In...

We studied remodeling and microcrack damage in specimens of Thoroughbred racehorse third metacarpal bone that had been subjected to monotonic or fatigue failure. We asked three questions. What effects does mechanical loading have on histologically observable microcrack damage? Are there regional variations in remodeling of the equine cannon bone, and do these variations correlate with mechanica...

alveolar ridge resorption has long been considered an unavoidable consequence of tooth extraction. while the extent and pattern of resorption is variable among individuals, there is a progressive loss of ridge contour as a result of physiologic bone remodeling. even today, with best modalities of tooth preservation, there is a group of elderly individuals who do not benefit from modern preventiv...

nitrogen containing bisphosphonate (n-bp) therapy is used extensively to treat osteoporosis and osteolytic bone lesions. recently, a special form of osteonecrosis limited to the maxillofacial skeleton has been discovered especially within those patients who are receiving either long-term n-bp therapy alone and/or associated with invasive dental procedure. bisphosphonates accumulate almost exclu...

Introduction: Beta calcium sulfate hemihydrate (BCSH), which is commonly known as “Gypsum plaster” has long been used as bone graft material because of its excellent biocompatibility and the ability for bone regeneration. Several methods have been used for the preparation of BCSH, including heat treatment of calcium sulfate dihydrate with water, application of inorganic acids or condensed inorg...

  Objective(s): Studies have reported that whole body vibration (WBV) played a vital role in bone remodeling. Circulating serotonin is also involved in negative regulating bone mass in rodents and humans. However, both WBV and inhibition of serotonin biosynthesis may suppress receptor activator of nuclear factor-kappaB ligand (RANKL)-induced osteoclastogenesis in vitro . The purpose of the ...

Abstract Ligamentum flavum cyst of the lumbar spine has seldom been described. The mechanism formation these cysts remains unknown, but it is thought to be part degenerative process. Although they are clearly visible on imaging studies, frequently wrongly diagnosed as ganglion or synovial cysts. Bone erosion rarely associated with this pathology. Most common symptom back and radicular pain due ...

Currently available implants for direct attachment of prosthesis to the skeletal system after transfemoral amputation (OPRA system, Integrum AB, Sweden and ISP Endo/Exo prosthesis, ESKA Implants AG, Germany) show many advantages over the conventional socket fixation. However, restraining biomechanical issues such as considerable bone loss around the stem and peri-prosthetic bone fractures are p...

conclusions alendronate may be considered a therapeutic option for improving the bone formation process and reducing resorption in different bone grafting procedures. further detailed studies should focus on dosage and time-dependent effects of alendronate on bone remodeling. results at 6 weeks, the bone area was significantly larger in the xenograft-alendronate group (33.0% ± 5.0%) than in the...