Overactive bladder is a highly prevalent clinical condition that is often caused by bladder outlet obstruction (BOO). Increased coupling of bladder smooth muscle cells (BSMC) via gap junctions has been hypothesized as a mechanism for myogenic bladder overactivity in BOO, although little is known about the regulatory system underlying such changes. Here, we report the involvement of basic fibrob...

The objectives of this study were to determine and compare the correlation of intravesical prostatic protrusion (IPP) and prostate volume (PV) with bladder outlet obstruction (BOO). This study was conducted in the department of urology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, between July 2009 to September 2010. Fifty benign prostatic hyperplasia (BPH) patients w...

Background: To detect the effect of hypoxia inducible factor mediated EMT in the mechanism of detrusor instability. Methods: A total of 49 patients with detrusor instability (DI) secondary to bladder outlet obstruction (BOO) were randomly chosen according to the urodynamic result as the study group. 36 patients with BOO proved with detrusor instability (DS) by urodynamic as control group. The d...

Background There is a lack of understanding the clinical significance detrusor contraction duration (DCD) measured on urodynamic studies (UDS). We aimed to identify patient characteristics, presenting symptoms and parameters associated with DCD in women. Methods Using single-institution database UDS (2015-2019), 405 female patients measurable contractions were identified. Baseline analyzed. Bla...

Hyun Jong Kang, Hyeon-Jeong Lee, Young-Hoon Jung, Soeun Jeon, Boo Young Hwang, Ji Seok Baik, Eun-Soo Kim, Jae-Young Kwon, Seekyo Kim. Med Biol Sci Eng 2023;6:90-4. https://doi.org/10.30579/mbse.2023.6.2.90

Using a model of the vertical structure of accretion discs, we calculate disc spectra across a range of system parameters for the helium-rich AM CVn cataclysmic variables, and investigate thermal instabilities in their discs. Applying a χ2-minimisation technique, predicted HeI and HI continuum and line profiles are compared with those observed for two such systems, AM CVn and CR Boo, to estimat...