Bovine pasteurellosis is known by a number of synonyms that are descriptive of the condition and are relevant in specific circumstances. The terms shipping fever, transit fever, bovine enzootic pneumonia, and bovine respiratory disease (BRD) complex are all very meaningful terms used to describe the disease. It is believed that in the United States, the losses to the beef and dairy industries f...

Clinafloxacin is a broad-spectrum fluoroquinolone that was originally developed and subsequently abandoned in the late 1990s as a human health antibiotic for respiratory diseases. The purpose of this study was to investigate the activity of clinafloxacin as a possible treatment for respiratory disease in cattle and pigs. Minimum inhibitory concentration (MIC) values were determined using Clinic...

I herby declare that the research described in this thesis and the thesis itself was composed and originated entirely by myself, except where otherwise stated. Genes controlling vaccine responses and disease resistance to respiratory viral pathogens in cattle. Veterinary Immunology and Immunopathology. (In press) Quantitative trait loci for variation in immune response to a Foot-and-Mouth disea...

The polymerase chain reaction (PCR) has been widely used for diagnosis of infectious diseases of domestic animals. Rapid detection of respiratory pathogens of cattle is useful for making therapeutic decisions. Therefore, we developed a new genetic-based method called droplet-real-time PCR, which can detect bovine respiratory syncytial virus (BRSV) within 10 min. Our droplet-real-time PCR marked...

including a lower sensitivity and greater delay before the result is available [7, 8]. The prompt and accurate detection of a respiratory virus infection in patients with underlying lung disease is important for a number of reasons. Anti-viral medications are sometimes indicated for patients with a suspected or confirmed respiratory viral infection, particularly RSV or influenza [9]. Some respi...

BACKGROUND Macrolides have received considerable attention for their anti-inflammatory and immunomodulatory actions beyond the antibacterial effect. These two properties may ensure some efficacy in a wide spectrum of respiratory viral infections. We aimed to summarize the properties of macrolides and their efficacy in a range of respiratory viral infection. METHODS A search of electronic jour...