نتایج جستجو برای: brain ischemia

تعداد نتایج: 541296  

Journal: :Methods 2003
Suzanne DeBow Frederick Colbourne

Temperature measurement and control are essential in most ischemia experiments. Hypothermia lessens ischemic brain injury whereas hyperthermia exacerbates it. A substantial number of ischemia studies rely solely on rectal temperature measurements during the insult. However, rectal temperature may not accurately reflect brain temperature especially during global ischemia. Furthermore, postischem...

2016
Lianshuang Zhang Xifeng Wang Xinghan Tian Wei Zhao Tongshen Liu Guoying Feng Heng Cai Jie Liu

This study was designed to investigate whether hydrogen administration can produce neuroprotective effects and its related molecular mechanism after brain ischemia reperfusion in rats. 36 Sprague-Dawley rats were randomly divided into sham group, ischemia reperfusion group and ischemia reperfusion hydrogen therapy group. Brain ischemia reperfusion injury was induced by a 2-hour left middle cere...

Journal: :iranian journal of pathology 2011
majid asadi-shekaari hassan eftekhar vaghefi masoud ezzat abadi pour vahid sheibani ali shams ara

background and objective: as one of the widely used drugs, aspirin (acetyl-salicylic acid, asa) plays an important role in stroke treatment and prevention. in a previous study, we demonstrated asa injection at 30 min after ischemia onset is neuroprotective. to determine whether the neurons protected by asa had a normal ultrastructure, hippocampal ca1 pyramidal neurons were examined by transmiss...

Journal: :Journal of experimental stroke & translational medicine 2010
Donald J Degracia

The general failure of neuroprotectants in clinical trials of ischemic stroke points to the possibility of a fundamental blind spot in the current conception of ischemic brain injury, the "ischemic cascade". This is the fourth in a series of four papers whose purpose is to work towards a revision of the concept of brain ischemia by applying network concepts to develop a bistable model of brain ...

Journal: :Journal of Clinical Investigation 2000

Journal: :Current Medicinal Chemistry 2015

SEYYED MASSOUD KHATAMI,

In addition to the liver, human hydatidosis has been reported in the lung, brain, abdominal viscera, muscles, and heart chambers. Infarction of the brain has also been documented. Arterial embolism of the lower extremities by hydatid cyst, however, is extremely rare. In the presented case, acute ischemia of the patient's left leg led to gangrene and amputation. Complete workup for localizat...

2014
Ruben S. Mirzoyan Tamara S. Gan'shina Denis V. Maslennikov Georgy I. Kovalev Ivan A. Zimin Boris M. Pyatin Nina I. Avdyunina Anna M. Kukhtarova Nelly G. Khostikyan Vahe S. Meliksetyan Cristina B. Alikhanyan Narine R. Mirzoyan

OBJECTIVES The influence of 5-hydroxyadamantane-2-on was studied on the rats' brain blood flow and on morphological state of brain tissue under the condition of brain ischemia. The interaction of the substance with NMDA receptors was also studied. METHODS Study has been implemented using the methods of local blood flow registration by laser flowmeter, [(3)H]-MK-801binding, and morphological e...

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