نتایج جستجو برای: brain natriuretic peptide ventricular dysfunction
تعداد نتایج: 876940 فیلتر نتایج به سال:
Historical perspective A series of experiments done in the mid 1950s established the heart as an endocrine organ. First, Kisch and colleagues detected secretory granules in guineapig atria. Henry and Pearce subsequently described increased urinary flow after balloon stretch of the canine left atrium. In an experiment done 25 years later, de Bold injected homogenised atrial tissue into rats and ...
BACKGROUND Pharmacological blockade of the renin-angiotensin system improves exercise tolerance in patients with left ventricular dysfunction, yet its impact on patients with systemic right ventricles (RVs) remains unknown. METHODS AND RESULTS A multicenter, randomized, double-blind, placebo-controlled, crossover clinical trial was performed to assess the effects of losartan on exercise capac...
UNLABELLED There has been a large confirmation over the last decades that stroke may produce cardiac changes (echocardiographic, electrocardiographic, enzymatic). In ischemic stroke, systolic dysfunction is associated with a high risk of mortality during hospitalization. A recent study demonstrated that cardiac diastolic dysfunction could also accompany acute stroke besides the systolic dysfunc...
We have isolated a cardiac natriuretic peptide of 5,000 d from atrial tissues from 500 rats and determined its amino acid sequence. The 5,000 d atrial natriuretic factor was elucidated to be a 45 amino acid peptide with the sequence of S-Q-D-S-A-F-R-I-Q-E-R-L-R-N-S-K-M- A-H-S-S-S-C-F-G-Q-K-I-D-R-I-G-A-V-S-R-L-G-C-D-G-L-R-L-F by sequencing the native peptide and its lysyl endopeptidase digests. ...
OBJECTIVES To assess the probability of left ventricular systolic dysfunction without echocardiography in patients from general practice. DESIGN Cross sectional study using multivariate regression models to examine the relation between clinical variables and left ventricular systolic dysfunction as determined by echocardiography. SETTING Three general practices in Copenhagen. SUBJECTS 215...
BACKGROUND In asymptomatic patients with ≥3+ mitral regurgitation and preserved left ventricular (LV) ejection fraction who underwent mitral valve surgery, we sought to discover whether baseline LV global longitudinal strain (LV-GLS) and brain natriuretic peptide provided incremental prognostic utility. METHODS AND RESULTS Four hundred and forty-eight asymptomatic patients (61±12 years and 69...
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