Parinari curatellifolia (Chrysobalanaceae) and Terminalia sericea (Combretaceae) have been traditionally used in Southern Highlands of Tanzania for treatment various infectious disorders. The present study aimed to evaluate antifungal activity the isolated compounds from plant species. ethyl acetate extract root barks were fractionated using column chromatography. structures established both 1D...

Malassezia is a genus of lipid-dependent yeasts. It is associated with common skin diseases such as pityriasis versicolor and atopic dermatitis and can cause systemic infections in immunocompromised individuals. Owing to the slow growth and lipid requirements of these fastidious yeasts, convenient and reliable antifungal drug susceptibility testing assays for Malassezia spp. are not widely avai...

Present study screened ten Cyanobacterial extracts for antimicrobial activity, cytotoxicity (against human cervical carcinoma cells Hela and SiHa) & GC-MS for chemical composition. Cyanobacterial extracts were subjected to Agar Well Diffusion Assay at concentration of 100μg. well -1 and incubated at 37 + 2 o C. Inhibition zone was measured in millimetres (mm) after 18-24 hour. Minimum inhibitor...

Comparison of MIC results obtained in different parts of the world is currently difficult because of variations in methods. In this study, cation-adjusted Mueller-Hinton broth, the NCCLS-recommended medium, was compared with Iso-Sensitest broth, which is widely used in Europe. Microbroth dilution testing, using the NCCLS procedure, was performed on 124 Gram-positive (staphylococci and enterococ...

Susceptibilities of 124 strains of Streptococcus pneumoniae to erythromycin and clindamycin were determined by the National Committee for the Clinical Laboratory Standards (NCCLS) broth microdilution method, with incubation for 20 to 24 h in ambient air and with modifications of this method by incubation for up to 48 h in air and CO2. Strains were also tested by agar dilution, E-test, and disk ...

Abstract Introduction/Objective Introduction: The emergence of antifungal resistance patients after long-term treatment shows an urgent need to develop new therapies. ability Candida albicans cells form biofilm is resistant many agents; it causes about 90% vaginal yeast infections. Farnesol has a critical regulatory (quorum-sensing) molecule in C. formation, phenomenon that may be relevant form...

Minimal inhibitory concentration of antimicrobials, determined by the broth microdilution method, requires visual assessment or absorbance measurement using a spectrophotometer. Both procedures are usually performed manually, requiring presence an operator to assess plates at specific time point. To increase throughput antimicrobial susceptibility testing, and concurrently convert into automati...