BACKGROUND The 12-item Health Survey (SF-12) was developed as a shorter alternative to the SF-36 for use in large-scale studies, particularly when overall physical and mental health are the outcomes of interest instead of the typical eight-scale profile. The main purpose of this study was to assess the validity of the Greek version of the SF-12. METHODS A stratified representative sample (N =...

Objective: To contribute to the validation of the revised BMI-MNA-SF and CCMNA-SF with regard to association and agreement with the full-MNA, considered as gold standard, in nursing homes in Spain. Design: Prospective analysis. Setting: Nursing homes. Participants: Eight hundred ninety five subjects aged 65 or older meeting inclusion criteria. Measurements: Correlation, diagnostic accuracy and ...

Scatter factor/hepatocyte growth factor (SF/HGF) is a pleiotropic cytokine that has been implicated in glioma invasion and angiogenesis. The SF/HGF receptor, MET, has been found to be expressed in neoplastic astrocytes as well as in endothelial cells of the tumor vasculature. Both SF/HGF and MET expression have also been described to correlate with the malignancy grade of human gliomas. However...

Hepatocyte growth factor/scatter factor (HGF/SF) is a multifunctional growth factor that promotes proliferation, motility, and morphogenesis in epithelial cells. Recently the HGF receptor, c-met protooncogene product, has been shown to be expressed in developing limb buds (Sonnenberg, E., D. Meyer, M. Weidner, and C. Birchmeiyer, 1993. J. Cell Biol. 123: 223-235), suggesting that some populatio...

In the design of circular patch antenna, the feed point locations SF=5, SF=6, SF=7 and SF=8 were selected and the simulated results compared and the optimum location adopted and implemented. The best feed point was located at SF=5mm where return loss RL is -37.81dB, followed by SF=6mm with return loss RL of -17.14dB and SF=7mm with return loss RL is -11.38dB. The feed point location at SF=8mm w...

Silk fibroin (SF) has been widely investigated in biomedical applications due to its biodegradability and biocompatibility. The objective of this work was to prepare SF spheres for drug delivery application. Drug-loaded SF spheres with and without polyethylene glycol diglycidyl ether (PEGDE) crosslinking were prepared by a water-in-oil emulsion solvent diffusion method. Blue dextran was used as...

Stock-flow (SF) systems involving the accumulation of a stock over time are pervasive in many areas of human life. However, people make consistent mistakes when regulating such systems, a phenomenon termed SF failure. We introduce holistic (global) versus analytic (local) processing as a cognitive mechanism underlying the hardly understood SF failure. Using a classic SF problem (department stor...

The inhibin alpha-subunit gene is expressed in the ovary, testis, adrenal, and pituitary. Because this pattern of expression corresponds to that of the orphan nuclear receptor, steroidogenic factor-1 (SF-1), we hypothesized that the inhibin alpha promoter might be regulated by SF-1. Expression of exogenous SF-1, in an SF-1 deficient cell line, caused modest stimulation of the inhibin alpha prom...

BACKGROUND Atrazine is a potent endocrine disruptor that increases aromatase expression in some human cancer cell lines. The mechanism involves the inhibition of phosphodiesterase and subsequent elevation of cAMP. METHODS We compared steroidogenic factor 1 (SF-1) expression in atrazine responsive and non-responsive cell lines and transfected SF-1 into nonresponsive cell lines to assess SF-1's...