SHIPLEY, REGINALD A., ETHEL BUCHWALD CHUDZIK, AUSTIN P. GIBBONS, KATHLEEN JONGEDYK, AND DEWEY 0. BRUMMOND. Hate of glucose tmnsformation in the rat by whole-body analysis after glucose-W. Am. J. Physiol. 213(5): 1149-l 158. 1967.-Rate of disposal of glucose in the normal fasted rat, as calculated by Stewart-Hamilton dilution principle after a single injection of glucose-L-W, was 0.22 mg glucose...

A method previously developed for the regiospecific synthesis of polysubstituted indolines and indoles has been investigated for its utility in organic synthesis. The method relies on the regiospecific generation of zirconocene-stabilized benzyne complexes from N-allyl-2-bromoaniline derivatives. These complexes undergo an intramolecular olefin insertion to provide 5,5,6-tricyclic indoline zirc...

The N-arylindole subunit is an important species in many biologically active and pharmaceutically important compounds, which display antiestrogen [1], analgesic [2], antiallergy [3], antimicrobial [4], and neuroleptic activity [5]. Although the traditional coppercatalyzed coupling of an aryl halide with a heteroatombased nucleophile, the Ullmann-type coupling reaction, has remained a standard m...

Alzheimer's disease (AD) is a progressive neurodegenerative disease with no cure till today. Aberrant activation of cell cycle regulatory proteins is implicated in neurodegenerative diseases including AD. We and others have shown that Cyclin dependent kinase 4 (Cdk4) is activated in AD brain and is required for neuron death. In this study, we tested the efficiency of commercially available Cdk4...

SWETT, J. E., EARL ELDRED, AND J. S. BUCHWALD. Somatotopic cord-to-muscle relations in efferent innervation of cat gastrocnemius. Am. J. Physiol. 2 19(3) : 762-766. 1970.-Motor innervation to the medial gastrocnemius muscle (MG) was examined in cats by stimulating natural rootlets and teased filaments of the ventral roots, and observing the location of contraction areas on the exposed muscle su...

Introduction. It was previously known that S contents were low in the two volatile depleted magmatic iron-meteorite groups IVA and IVB. Group IID, with 21 members, the fourth largest magmatic group, also has a low S content but has high contents of other volatiles. We suggest that this surprising juxtaposition is best understood by two episodes of core formation, with the IID irons forming from...

2 Fukuda K , Straus SE , Hickie I , et al . The chronic fatigue syndrome : a comprehensive approach to its definition and study [ J ] . A nn Intern Med , 1994 , 121 ( 12 ) : 953-959 . 3 郑筱萸 . 中药新药临床研究指导原则 [ M ] . 北京 : 中国 医药科技出版社 , 2002 . 361-392 . 4 Kawakami N , Iwata N , F ujihara S , et a l . P revalence of chronic fatigue syndrome in a community population in Japan[ J ] . Tohoku J Exp Med , ...

Correspondence should be addressed to Adam B. Buchwald, Department of Psychological and Brain Sciences, Speech Research Laboratory, Indiana University, Bloomington, IN 47405, USA; E-mail: [email protected] This research was supported by the IGERT Program in the Cognitive Science of Language at Johns Hopkins University, National Science Foundation Grant 997280. Preparation of the paper was su...

Reaction of [Pd(PPh(3))(4)] with 1,1-dichloro-2,3-diarylcyclopropenes gives complexes of the type cis-[PdCl(2)(PPh(3))(C(3)(Ar)(2))] (Ar = Ph 5, Mes 6). Reaction of [Pd(dba)(2)] with 1,1-dichloro-2,3-diarylcyclopropenes in benzene gave the corresponding binuclear palladium complexes trans-[PdCl(2)(C(3)(Ar)(2))](2) (Ar = Ph 7, p-(OMe)C(6)H(4)8, p-(F)C(6)H(4)9). Alternatively, when the reactions ...

Previous studies of neuron changes during conditioning have involved either surgical and paralytic restraints (Yoshii and Ogura 1960; Kamikawa et al. 1964) or free behavior in chronic animals (Buchwald et al. 1966; Travis and Sparks 1967; Ellison et al., in press). The search for neural traces of critical changes in learning has thus been clouded by the surgical and paralytic procedures or conf...