Linear IgA bullous dermatosis (LABD) is a rare autoimmune bullous disease that can either occur without any apparent cause or be induced by the administration of certain drugs, the most common of which is vancomycin. We present a case of a 45-year-old woman who was diagnosed with vancomycin-induced LABD by the presence of a characteristic linear band of IgA along the basement membrane zone on d...

We examined small airway morphometry from resected lung specimens in 25 patients with severe emphysema undergoing lung volume reduction surgery (LVRS) and correlated their pathologic findings to changes in FEV(1) 6 months after LVRS. Patients were classified into two groups: responders had a more than 12% and a more than 200-ml change in FEV(1) at 6 months, and nonresponders had 12% or less and...

Giant lung bullae have a large impact on respiratory mechanics1,2 and make ventilator management difficult in patients undergoing mechanical ventilation. The pathogenesis of lung bullae is varied. COPD-related emphysematous bullae are the most common type of lung bullae, whereas ventilator-associated lung bullae are rare. Treatment considerations include therapy for underlying disease, ventilat...

Amyloidosis is a systemic disease involving multiple orchain lambda-type multiple myeloma and combined amyloid gans such as heart, kidney, and skin. It can also present with diverse skin lesions such as pinch hemorrhages and maculopapular eruptions; however, hemorrhagic bullous lesions are very rare. Here, I introduce a case of bullous amyloidosis undergoing hemodialysis for the treatment of en...

OBJECTIVE Sub-epidermal bullous disorders belong to immunobullous diseases which develop as a result of autoantibody action against epidermal basement membrane proteins. Clinically, they are tense bullae and do not rupture easily. They are classified into various forms based on histopathology and direct immunofluorescence patterns. This study was undertaken to assess the incidence of various su...

Diffuse cutaneous mastocytosis, the most rare form of cutaneous mastocytosis, often manifests as bullous lesions. Although cutaneous mastocytosis should be included in a differential diagnosis for pruritic skin lesions in children, early diagnosis of the disease is not easy due to its rare occurrence. A 17-month-old boy presented with recurrent itchy bullous skin lesions. He had been treated as...

Linear IgA bullous dermatosis (LABD) is an autoimmune disease characterized by blisters on the skin and mucous membranes. Polycyclic, grouped bullae on cutaneous skin are the most characteristic clinical feature of LABD. Lesions are often indistinguishable from bullous pemphigoid or may resemble dermatitis herpetiformis. Oral lesions may be seen in 5% to 70% of patients with LABD, and in some c...

the aim of this retrospective statistical study was to determine the prevalcence and frequency of age and sex distributions of pemphigus disease. pemphigus disease classified as autoimmune bullous dermatoses which is a chronic mucocutaneous disease.this study was performed in razi hospital and department of oral pathology of dental school, tehran university of medical sciences. the most frequen...

n 18-year-old white woman was admitted complaining ofright-sided chest pain offive days duration. The pain was sharp and acute in onset, pleuritic in nature, and felt diffusely throughout the right chest. She had low grade fever and generalized weakness. The patient denied shortness of breath, cough or bloody sputum. There was no history of asthma or pneumonia, and she was a nonsmoker. Her past...