Current evidence suggests that the expression of the tyrosine kinase p210bcr/abl in chronic myelogenous leukemia (CML) may directly induce the initial phase of granulocytic hyperplasia. However, the dysregulation of additional genes appears to be required for transition to the acute leukemic phase, as inferred by the appearance of recurrent secondary cytogenetic abnormalities in the majority of...

Streptomyces are considered the most potential microbes with ability to produce antimicrobial and anticancer agents. These bacteria found mostly in soil across globe play a pivotal role material recycling processes. Isolation of Vietnam has been conducted for years. However, there few investigations on protected regions which have very little exchanging activities. This project aims explore res...