The effects of chronic phosphate depletion on renal tubular function were evaluated by micropuncture and free water clearance studies in the dog. Proximal tubular punctures demonstrated that chronic hypophosphatemia led to a reduction in ratio of tubular fluid to plasma inulin in late superficial tubular from 1.59+/-0.08 in control animals to 1.29+/-0.06 in phosphate-depleted dogs, with proport...

Background: This study sought to explore the clinical effects of vancomycin-loaded calcium phosphate cement (CPC) in treatment chronic osteomyelitis.

BACKGROUND/AIMS The associations between phosphate, calcium, and intact parathyroid hormone (PTH) levels and composite cardiovascular end points have been studied. This study examined the associations of these markers with myocardial infarction (MI) and stroke separately. METHODS This is a longitudinal study on 65,849 hemodialysis patients from the Japan Renal Data Registry. Patients with pri...

Vaccination to protect against human infectious diseases may be enhanced by using adjuvants that can selectively stimulate immunoregulatory responses. In a murine model, a novel nanoparticulate adjuvant composed of calcium phosphate (CAP) was compared with the commonly used aluminum (alum) adjuvants for its ability to induce immunity to herpes simplex virus type 2 (HSV-2) and Epstein-Barr virus...

Titrimetric estimation of calcium with disodium ethylene diamine tetra-acetate (E.D.T.A., sodium edetate), as performed on serum (Baron and Bell, 1957), cannot be applied directly to most other biological specimens because of their high concentration of phosphate. A high ratio of phosphate to calcium in the material titrated causes a drawnout and inaccurate endpoint. A rapid procedure for calci...

Novel microcarriers consisting of calcium phosphate cement and alginate were prepared for use as three-dimensional scaffolds for the culture and expansion of cells that are effective for bone tissue engineering. The calcium phosphate cement-alginate composite microcarriers were produced by an emulsification of the composite aqueous solutions mixed at varying ratios (calcium phosphate cement pow...

Background and Aim: Several reports have been published on the successful application of various bone substitute materials (BSM). Appropriate physiologic and histologic characteristics and reactions of these materials against host cells are critically important. In this study, the biocompatibility of a new bone substitute material has been evaluated. Methods and Materials: In this experime...

background and aims. the aim was to evaluate the effect of casein phosphopeptide–amorphous calcium phosphate (cpp-acp) on microtensile bond strength (µtbs) to carious affected dentin (cad) using etch-and-rinse and self-etch adhesive systems. materials and methods. the occlusal surface of 32 human molars with moderate occlusal caries was removed. infected dentin was removed until reaching cad an...

background:dental caries is associated with oral pathogenes and streptococcus mutans (s. mutans)is one of the primary cariogenic organisms. the aim of this clinical study was to evaluate the effect of sugar free chewing gum containing casein phosphopeptide-amorphous calcium phosphate(cpp-acp) and xylitol on salivary streptococcus mutan.   m aterials and methods: 60 dental students, who voluntee...

Since studies in animals and humans have shown that parathyroid hormone can stimulate bone formation and increase trabecular bone, and patients with primary and secondary hyperparathyroidism may exhibit osteosclerosis, we evaluated the effect of short-term administration of human parathyroid hormone, hPTH-(1--34), in patients with osteoporosis. Six patients with osteoporosis underwent detailed ...