Abstract Background Our present study aimed to evaluate the effect of calcium phosphate nanoparticles in chlorohexidine paste on odontogenic differentiation human dental pulp stem cells. The cells (HDPSCs) were examined for viability and proliferation via trypan blue stain test MTT assay. This was followed by evaluating alkaline phosphatase assay detecting Dentin matrix protein (DMP-1) marker i...

Neuroblastoma (NB) is a common solid tumor in children and infants, the formation regression of which closely linked to tumor-host immune relationship. Stimulator interferon genes (STING) agonists, particularly cyclic dinucleotide (CDN), have promising potential NB therapy by generating innate adaptive stimulation, thus leading control. CDN delivery vivo challenging due negative charge, hydroph...

The effect of the introduction charged aluminum oxyhydroxide (AO) nanoparticles into porous coatings from calcium phosphate formed by micro-arc oxidation on their electrical potential and structure was studied. modification resulted in changes morphology elemental composition coatings. selection coating functionalization parameters obtaining homogeneously distributed form agglomerates, providin...