Capillary electrophoresis (CE) with indirect UV detection is an interesting analytical method for the analysis of drugs and pharmaceuticals. Good and reproducible capillary quality is needed to develop robust methods and to facilitate method transfer in CE. It is widely accepted that preconditioning procedures are indispensable in capillary electrophoresis in order to achieve reproducibility of...

The steady-state exchange of inert gases across an in situ canine trachea has recently been shown to be limited equally by diffusion and perfusion over a wide range (0.01-350) of blood solubilities (betablood; ml . ml-1 . atm-1). Hence, we hypothesize that the exchange of ethanol (betablood = 1,756 at 37 degrees C) in the airways depends on the blood flow rate from the bronchial circulation. To...

The authors emphasize the need for the development of non-invasive objective methods for the study of retinal circulation under physiologic or pathologic conditions. Clinical methods embrace the use of blue field entoptic phenomenon (that estimates leucocy tes circulating in the peri-foveal capillary bed), Laser-Doppler speedometer (that allows the mea surement of erythrocyte.velocity in retina...

OBJECTIVES During the first 48 hours after placement, an autograft "drinks" nutrients and dissolved oxygen from fluid exuding from the underlying recipient bed ("plasmatic imbibition"). The theory of inosculation (that skin grafts subsequently obtain nourishment via blood vessel "anastomosis" between new vessels invading from the wound bed and existing graft vessels) was hotly debated from the ...

the phenomenological model of khossravi and connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. the accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (apmd). the obtained apmd for correlative and predictive studies ...

Costello O, West JB. Short-term reversibility of ultrastructural changes in pulmonary capillaries caused by stress failure. J Appl Physiol 1992; 73: 1150–8. [12] Kay JM, Edwards FR. Ultrastructure of the alveolar-capillary wall in mitral stenosis. J Pathol 1973; 111: 239–45. [13] Lee YS. Electron microscopic studies on the alveolar-capillary barrier in the patients of chronic pulmonary edema. J...