BACKGROUND Cellulose acetate phthalate (CAP) in soluble form blocks coreceptor binding sites on the virus envelope glycoprotein gp120 and elicits gp41 six-helix bundle formation, processes involved in virus inactivation. CAP is not soluble at pH < 5.5, normal for microbicide target sites. Therefore, the interaction between insoluble micronized CAP and HIV-1 was studied. Carbomer 974P/BufferGel;...

Magnetohydrodynamic mixing was evaluated as an alternative to conventional high shear (HSM) in the preparation of carbomer hydrogels containing 1.22 wt% Carbopol® 980 NF. Neutralization dispersion (pH = 2.74) with triethanolamine (TEA) enabled adjust pH mixture and tune viscosity hydrogel. Using HSM, this approach limited 0.2 TEA 3.83) gel became too viscous recirculation flow dropped from 12 0...

An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares comparison with the convention one adjuvanted Al-hydra gel saponin. Such purpose established by 0.5% to EHV-1. The applied quality control tests carried out on such revealed that it is free from foreign contaminants, safe pregnant mice potent indu...

the present study involves preparation and evaluation of gastric-mucoadhesive microparticles with metformin hydrochloride as model drug for prolongation of gastric residence time. the microparticles were prepared by the emulsification solvent evaporation technique using polymers of carbomer 934p (c) and ethylcellulose (ec). the microparticles were prepared by emulsion solvent evaporation method...

function, 51 Riemann integral, 51 adjoint bilinear form, 65 almost separably valued, 53 Ascoli Theorem, 8 Banach space reflexive, 6 separable, 2 Banach-Steinhaus Theorem, 5 Bessel’s inequality, 9 biharmonic, 61 bilinear form, 55, 58 bounded, 58 strongly positive, 58 Bochner-Pettis Theorem Theorem, 53 Bounded Inverse Theorem, 6 Calculus in W 1,p(I;X) Theorem, 54 Campanato ’63 Theorem, 86 Campana...

Coral reefs are subject to a high frequency of recurrent biological and physical disturbances. The temporal and spatial scales of these are often large and difficult to study, so that most of our knowledge of disturbances on coral reefs comes from investigations conducted at one or a few sites, over short periods of time. We argue that studying single events in isolation can be misleading and t...

Fusidic acid 1% and chloramphenicol 0.5% eye drops were in a randomized, single-blind manner given as a one-week treatment to out-patients with acute, purulent conjunctivitis. A clinical success was recorded in 84% (102/121) of patients receiving fusidic acid and in 81% (104/129) of patients receiving chloramphenicol. More patients (14%) receiving chloramphenicol complained of trivial side effe...