To improve production of functional fully gamma-carboxylated recombinant human clotting factor IX (r-hFIX), cell lines stably overexpressing r-hFIX have been engineered to also overexpress proteins of the gamma-carboxylation system. Here we demonstrate that siRNA silencing of calumenin, an inhibitor of the gamma-carboxylation system, enhances production of functional r-hFIX produced by engineer...

ABSTRACT The ornamental sunflower has great importance in the floriculture sector due to color and vitality of its flowers. However, production quality flowers decrease under salt stress, which can be mitigated with paclobutrazol application. objective present study was evaluate effects different application methods ‘Sol Noturno’ irrigated brackish waters. experimental design randomized blocks ...