Background: The most important strategy of the immune system against pathogens is producing active oxygen intermediates with sidelong consequence of oxidative stress induction in body. Probiotics and selenium have recently been proven to be powerful antioxidants that help boost the immune system. Hence, the aim of this study was to investigate the antioxidant effects of Sac...

(ABSTRACTOxygen free radical mediated tissue injury is implicated as a major factor in the pathogenesis of the long term complications seen in the premature infant, and direct evidence of their role in the development of these long term problems is lacking. A prospective observational study of 78% of very low birthweight infants admitted to a level III neonatal intensive care unit in 1992 was u...

This study was conducted to investigate the effect of nano-selenium (nano-Se) on performance, meat quality, immune function, oxidation resistance, and tissue selenium content in broilers. A total of five hundred forty 1-d-old male Arbor Acres broilers were randomly allotted to 1 of 5 treatments with each treatment being applied to 6 replicates of 18 chicks. The 5 treatments consisted of corn-so...

We investigated oxidative stress in human postmortem frontal cortexfrom individuals characterized as mild cognitive impairment (n= 8), mild/moderate Alzheimer disease (n = 4), and late-stage Alzheimer disease (n = 9). Samples from subjects with no cognitive impairment (n = 10) that were age- and postmortem interval-matched with these cases were used as controls. The short postmortem intervalbra...

Adequate dietary iodine supplies and thyroid hormones are needed for the development of the central nervous system (CNS) and brown adipose tissue (BAT) function. Decreases in plasma thyroxine (T4) concentrations may increase the requirement for the selenoenzymes types I and II iodothyronine deiodinase (ID-I and ID-II) in the brain and ID-II in BAT to protect against any fall in intracellular 3,...

We have purified two isoenzymes of glutathione S-transferase from bovine retina to apparent homogeneity through a combination of gel-filtration chromatography, affinity chromatography and isoelectric focusing. The more anionic (pI = 6.34) and less anionic (pI = 6.87) isoenzymes were comparable with respect to kinetic and structural parameters. The Km for both substrates, reduced glutathione and...

Submit Manuscript | http://medcraveonline.com System; DM: Diabetes Mellitus; FABPs: Fatty Acid Binding Proteins; FAS: Fatty Acid Synthase; GPx: glutathione Peroxidase; GSH: Reduced Glutathione; GSH-ST: Glutathione-S-Transferase; HbA1c: Glycosylated Haemoglobin; HDAC: Histone Deacetylase; HDL-C: High-Density Lipoprotein-C; HIV: Human Immunodeficiency Virus; i.g.: Intragastric; i.p.: Intraperiton...

Myocardial infarction is a major public health concern and the leading cause of death throughout the world. The present study investigates the ability of Aegle marmelos fruit extract to prevent pathological changes and oxidative stress after isoproterenol induced myocardial infarction in rats. In vitro studies showed that Aegle marmelos fruit extract possesses antioxidant activity. Administrati...

Free radical-mediated oxidative stress has been implicated in the etiopathogenesis of several autoimmune disorders. Hypothyroidism in humans is widely believed to impair health. The biochemical factors mediating decline in health, however, are poorly elucidated. Pathological consequences of hypothyroidism point to a high potential for antioxidant imbalance. The study population consisted of 60 ...

BACKGROUND An oxidative stress has been reported in patients with chronic renal failure (CRF) treated by haemodialysis. To our knowledge, only scant information is available concerning CRF patients treated by continuous ambulatory peritoneal dialysis (CAPD) with regard to their redox and nutritional status. METHODS The oxidative stress and the biological nutritional status were evaluated in 2...