Generalized tonic-clonic seizures (GTCS) are the main risk factor for sudden unexpected death in epilepsy (SUDEP). Also, among several mechanisms underlying SUDEP there is cardiac dysfunction. So, we aimed to evaluate impact of number on heart function and morphology rats with epilepsy. Rats were randomized into three groups: Sham (without epilepsy), 5 S, 10 S groups, referred as a total or GTC...

echocardiography plays a fundamental role in the evaluation of patients with an intracardiac mass. the ability to distinguish tissue characteristics, location, attachment, shape, size, and mobility non-invasively, quickly, and without the use of ionizing radiation makes echocardiography the ideal diagnostic modality. with careful attention to mass location and morphology, and appropriate applic...

The fatality rate for pediatric population with complex congenital cardiac disease has decreased as a result of improvements in surgical techniques and conservative management [1]. Therefore, more patients are presenting non-cardiac surgeries adults history [2]. For individuals single ventricle physiology, the fontan procedure is palliative operation that reroutes systemic venous return to pulm...

Rainbow trout remain active in waters that seasonally change between 4°C and 20°C. To explore how these fish are able to maintain cardiac function over this temperature range we characterized changes in cardiac morphology, contractile function, and the expression of contractile proteins in trout following acclimation to 4°C (cold), 12°C (control), and 17°C (warm). The relative ventricular mass ...

6 List of original papers 7 List of abbreviations 8 Introduction 9 Cardiac cellular electrophysiology 12 Recording cardiac electricity 16 Electrocardiography (ECG) 16 Vectorcardiography (VCG) 16 Pacemaker treatment 20 Sick Sinus Syndrome 21 Hypertrophic Obstructive Cardiomyopathy (HOCM) 21 Wolff-Parkinson-White Syndrome (WPW syndrome) 22 Aims 23 Material and Methods 24 Studies I and II 24 Study...