INTRODUCTION Androgen deprivation therapy (ADT) for advanced prostate cancer can be associated with side effects which may negatively impact quality of life (QoL) and induce serious medical problems. AIM The aim is to give practical recommendations on how to monitor and counsel patients and effectively manage side effects based on relevant original articles, review articles and abstracts. R...

In many forms of erectile dysfunction (ED), cardiovascular risk factors, in particular arterial hypertension, seem to be extremely common. While causes for ED are related to a broad spectrum of diseases, a generalized vascular process seems to be the underlying mechanism in many patients, which in a large portion of clinical cases involves endothelial dysfunction, ie, inadequate vasodilation in...

BACKGROUND An array of risk factors has been associated with cardiovascular diseases, and developing nations are becoming disproportionately affected by such diseases. Cardiovascular diseases have been reported to be highly prevalent in the Mexican population, but local mortality data is poor. The Mexican side of the US-Mexico border has a culture that is closely related to a developed nation a...

Cardiovascular diseases are a frequent comorbid condition in patients with type 2 diabetes mellitus (t2DM). This problem tends to remain acute because of the progression t2DM, which increases chances cardiovascular events. Medicine today has range innovative hypoglycemic drugs, proved their safety and effectiveness towards system. However, high mortality demonstrates that medication is not enou...

Recent clinical trials raised concerns regarding the cardiovascular toxicity of selective cyclooxygenase-2 (COX-2) inhibitors. Many active dietary factors are reported to suppress carcinogenesis by targeting COX-2. A major question was accordingly raised: why has the lifelong use of phytochemicals that likely inhibit COX-2 presumably not been associated with adverse cardiovascular side effects....

Diabetes mellitus is one of the most common modifiable risk factors for coronary artery disease, and its prevalence is rising globally. Persistent hyperglycemia has a well-established cardiovascular risk, and its treatment plays an important role in the prevention of future cardiovascular events. While we improved microvascular complications such as retinopathy, nephropathy, and neuropathy by s...

Justin G. Reeves, MD, John S. Kim, MD, Max B. Mitchell, MD, Anthony C. McCanta, MD, FHRS From the Department of Cardiovascular Surgery, School of Medicine, Children’s Hospital Colorado, Aurora, Colorado, University of Colorado Denver, Denver, Colorado, Department of Pediatrics, School of Medicine, Children’s Hospital Colorado, Aurora, Colorado, Department of Cardiovascular Surgery, School of Me...

We demonstrate the close relationship between a conspicuous ocular pulse amplitude and severe underlying cardiovascular disease. Two otherwise symptom-free glaucoma patients without any previously diagnosed underlying cardiovascular pathology but with a conspicuous ocular pulse amplitude and who underwent routine examinations in our glaucoma department were referred to the appropriate specialty...

The selective COX-2 inhibitors (coxibs) were originally developed to minimise the adverse effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) while maintaining the same analgesic and anti-inflammatory properties. Many large studies confirmed the improved gastric side effect profile of coxibs compared with non-selective NSAIDs; however, reports of increased cardiovascular morb...

Most medications act best when patients take them; and this appears to be the case also for antihypertensive drugs. Unfortunately, there is evidence that patients stop taking treatment that is intended to be taken lifelong. This is unfortunate and will reduce the potential preventive effects of their medication. Thus, adherence to antihypertensive medication is inversely related to cardiovascul...