Debrisoquin hydroxylase (CYP2D6) is a cytochrome P450 enzyme that catalyzes the metabolism of > 30 commonly prescribed medications. Deficiency in CYP2D6 activity, inherited as an autosomal recessive trait, was found to be significantly less common in American blacks (1.9%) than whites (7.7%). To determine the genetic basis for this difference, inactivating CYP2D6 mutations were assessed by alle...

Contrary to research that suggests Blacks can only be reached effectively with Black-oriented media, this research demonstrates that there appears to be a subset of the Black population that can be reached equally well with Whitetargeted media as they can with Black-targeted media. The study findings confirm expectations that Blacks’ differential responses to race-targeted Web sites are mediate...

Spin-transfer torque (STT) switching demonstrated in submicron sized magnetic tunnel junctions (MTJs) has stimulated considerable interest for developments of STT switched magnetic random access memory (STT-MRAM). Remarkable progress in STT switching with MgO MTJs and increasing interest in STTMRAM in semiconductor industry have been witnessed in recent years. This paper will present a review o...

* This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education, Science and Technology(2010-0021897). Abstract As the power dissipation has become one of the critical design challenges in a sensor network environment, nonvolatile memories such as STT-MRAM and flash memory will be used in the next generat...

BACKGROUND The mechanism of enhanced vascular reactivity in young blacks, which may play a part in the development of hypertension, has not been defined. To determine the contribution of blunted vasodilatation mediated by beta 2-adrenergic receptors to this phenomenon, we compared forearm blood-flow responses to isoproterenol in young black and white normotensive men. METHODS We used venous-o...

We suggested a method for localization of ischemic lesions from difference integral body surface potential maps (IBSPMs) computed by subtraction of IBSPM without manifestation of ischemia from the IBSPM during ischemia that can be obtained at rest and during the stress test. In this work the possible changes in IBSPMs of healthy subjects with increasing HR were studied. BSPMs were measured duri...

Differences in cellular Na+ and K+ regulation may relate to the pathogenesis of essential hypertension and the predisposition of blacks to this disease. To explore these tenets, we examined several aspects of cellular Na+ homeostasis in serially passed, cultured skin fibroblasts from 30 subjects (15 hypertensive blacks and whites and normotensive subjects matched for sex, age, and race.) Fibrob...

Normative standards are provided for permanent tooth mineralization stages for blacks and whites of the middle southern United States. The data cover tooth development from 3.5 to 13 years of age. Females develop more rapidly than males, and blacks are nearly twice as sexually dimorphic (7.2%) as whites (3.7%). Within each sex, blacks achieve mineralization stages significantly earlier, by abou...

Acropora and Porites corals are important reef builders in the Indo-Pacific and Caribbean. Bacteria associated with mucus produced by Porites spp. and Acropora spp. from Caribbean (Punta Maroma, Mexico) and Indo-Pacific (Hoga and Sampela, Indonesia) reefs were determined. Analysis of pyrosequencing libraries showed that bacterial communities from Caribbean corals were significantly more diverse...