Remineralization of demineralized dentin lesions adjacent to glass-ionomer cements (GICs) has been reported in the literature. This study tested the hypothesis that a strontium-based GIC can remineralize completely demineralized dentin by nucleation of new apatite crystallites within an apatite-free dentin matrix. Human dentin specimens were acid-etched, bonded with Fuji IXGP, and immersed in a...

PURPOSE The purpose of this study was to evaluate the clinical and radiographic outcomes of a bioactive tricalcium silicate [Ca3SiO5]-based dentin substitute and a light-activated calcium hydroxide [Ca(OH)2]-based liner as indirect pulp treatment (IPT) interventions for vital primary molars with carious lesions approaching the pulp. METHODS Eighty children, aged four to eight years old, with ...

Gap junctions are composed of transmembrane proteins belonging to the connexin family. These proteins permit the exchange of mall regulatory molecules directly between cells for the control of growth, development and differentiation. Although the presence of gap junctions in teeth has been already evidenced, the involved connexins have not yet been identified in human species. Here, we examined...

This study was undertaken to evaluate the effect of caries detector dyes and/or cavity cleanser on composite bonding and etching patterns of enamel and dentin. One hundred and eight non-carious premolars were divided into six groups according to the enamel and dentin pretreatment investigated. The different pretreatment were as follows: Group I: teeth with prophylaxis only, Group II: Sable seek...

This study was planned to investigate the remineralization potential of the inner carious dentin layer preserved under adhesive resin restoration in comparison with that under cement filling. Dentin caries models were artificially produced in vivo with acid on the Class V cavity floors of 25 bilateral tooth pairs from 3 monkeys. Thirteen cavity pairs were filled with adhesive composite and twel...

This is a retrospective clinical study of 360 teeth diagnosed with pulpitis and treated locally with a combination of three antibacterial drugs (ciprofloxacin, metronidazole and minocycline, “3Mix-MP”) without a pulpectomy procedure. Consecutive patients with a clinical diagnosis of pulpitis had pre-operative factors collected (spontaneous pain, pulp exposure, depth of carious lesion) and were ...

Cadherins are calcium-dependent cell adhesion molecules involved in the regulation of various biological processes such as cell recognition, intercellular communication, cell fate, cell polarity, boundary formation, and morphogenesis. Although previous studies have shown E-cadherin expression during rodent or human odontogenesis, there is no equivalent study available on N-cadherin expression i...

An important issue prior to restorative or endodontic treatment of carious teeth is the assessment of the different conditions of each individual case. This relates to the static, anatomical considerations of the location of the caries lesion, as well as the dynamic activity and extent of the carious process. Moreover, the restorative treatment may be carried out for prosthetic or cosmetic purp...

the aim of this study was to compare the level of agreement between four operators with different levels of experience for two methods of detecting secondary enamel and dentin carious lesions in composite restored teeth.sixty teeth of 40 patients with with secondary carious lesions in the composite resin were selected. the teeth were examined by two methods; visual inspection and a laser fluore...

Objective: This study evaluated the effects of alternative self-etch application modes on resin-dentin microtensile bond strength (µTBS) three commercially available “no wait” concept universal adhesives. Materials and methods: In this extracted impacted non-carious human third molars were used. The flat surfaces prepared in mid-coronal dentin with a 600-grit SiC paper. adhesives that used are ...