Extremely low frequency magnetic fields (ELF-MFs) have been classified as possibly carcinogenic to humans by the International Agency for Research on Cancer. The authors investigated, in a population-based casecontrol study in Germany, if children whose parents were exposed preconceptionally at work to ELF-MFs had an increased risk of developing cancer. Cases aged 0–14 years were ascertained fr...

The xeroderma pigmentosum group C (XPC) gene plays a significant role in DNA damage recognition during nucleotide excision repair process. Polymorphisms of the XPC gene have been analyzed in numerous casecontrol studies to evaluate bladder cancer risk attributed to XPC genetic variation; however, published data on the association between XPC rs2228001 A/C and bladder cancer risk are inconclusiv...

Autoimmune diseases are a heterogeneous group of disorders affecting different organs and tissues whose incidence are increasing worldwide. New tools, such as genome-wide association studies, have provided evidence for new susceptibility loci and candidate genes in the disease process including common susceptibility genes involved in the immunological synapse and T cell activation. Close linkag...

Methods: A prospective multicenter study was conducted to determine the frequency and patient outcomes of medication-related hospital admissions. A casecontrol design was used to determine risk factors for potentially preventable admissions. All unplanned admissions in 21 hospitals were assessed during 40 days. Controls were patients admitted for elective surgery. Cases and controls were follow...

Occupations with mineral oil exposure have been associated with bladder cancer in population-based casecontrol studies. The authors report results from the first cohort study to examine bladder cancer incidence in relation to quantitative exposures to metalworking fluids (MWFs), based on 21,999 male Michigan automotive workers, followed from 1985 through 2004. Cox regression was used to estimat...

The results from studies of loud noise exposure and acoustic neuroma are conflicting. A population-based casecontrol study of 451 acoustic neuroma patients and 710 age-, sex-, and region-matched controls was conducted in Sweden between 2002 and 2007. Occupational exposure was based on historical measurements of occupational noise (321 job titles summarized by a job exposure matrix) and compared...

We reviewed 27 published studies examining a possible association between sensory (visual or hearing) impairment and late-life psychosis with paranoid features. A majority of these investigations supported the postulated association between hearing impairment and late-onset schizophrenia or paranoid disorder. Many of the published studies, however, had important methodological limitations. In a...

background: diabetes mellitus (dm) is a health concern which leads to complications such as retinopathy. pakistan has 6.9 million people living with dm and this toll will be doubled by 2025. objective: to determine serum il-6 and il-17 of type 2 diabetes mellitus (t2dm) patients with retinopathy. methods: in this cross-sectional casecontrol study, 212 subjects enrolled which were categorized in...

background: angiotensin i converting enzyme (ace) is a zinc metalloproteinase, converts ang-i to ang- ii, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. objective: to investigate the relationship between ace i/d polymorphism and type 2 diabetes in 261 iranian casecontrol pairs. methods: 170 patients (85 type 2 diabetics with nephropathy a...

The rapid increase followed by a leveling off in the incidence of non-Hodgkin lymphoma (NHL) in the United States and Europe in the last half of the 20th century4,5 has largely remained unexplained, a situation that has fascinated and frustrated a generation of lymphoma researchers. This state of affairs is likely due in part to a multifactorial etiology and the heterogeneous nature of this mal...