BACKGROUND Mammary tumours frequently develop in female domestic cats being highly malignant in a large percentage of cases. Chemokines regulate many physiological and pathological processes including organogenesis, chemotaxis of inflammatory cells, as well as tumour progression and metastasization. In particular, the chemokine/receptor pair SDF-1/CXCR4 has been involved in the regulation of me...

It has been shown (2) that, in those DBA breed ing females in which the nipples on the right side were blocked, an increased number of mammary tumors occurred at a younger age on the blocked right side, as compared to the intact left side. It was thought that milk stagnation was responsible for the increased tumor incidence. Several investigators (1,3) observed that mam mary glands of high tumo...

Forty-four multiparous, mammary tumor-free, SpragueDawley rats, 10 months old, were divided into two groups as follows: Group 1, sham-operated controls; and Group 2, bilateral electrolytic lesions placed in the median eminence area of the hypothalamus. After 25 weeks, the animals were killed, the number of palpable mammary tumors was determined, and blood was withdrawn for prolactin analysis by...

Intranuclear eosinophilic inclusion bodies were seen in the lactiferous duct and sinus epithelium of mammary tissues collected from a cow with clinical mastitis. Transmission electron microscopy revealed herpesvirus particles in these cells. Immunolabeling against anti bovine herpesvirus type 4 (BHV-4) rabbit serum was detected in nuclei that had intranuclear inclusion bodies. In addition, BHV-...

The mammary gland of laboratory rodents is an important organ for the evaluation of effects of xenobiotics, especially those that perturb hormonal homeostasis or are potentially carcinogenic. Mammary gland cancer is a leading cause of human mortality and morbidity worldwide and is a subject of major research efforts utilizing rodent models. Zymbal's, preputial, and clitoral glands are standard ...

It has recently been shown, in experiments on lactating rats with hypothalamic lesions, that milk can be expressed from the mammary glands of rearing-failed, lesioned rats by weak palpation even 10 days after the operation when vigorous suckling by young continued, and that a considerable amount of milk is obtained from mammary glands of these lesioned rats by the regular administration of oxyt...

Dirofilariasis is a transmissible zoonotic biohelminthiasis caused by nematodes that parasitize the lymphatic system and subcutaneous tissue. This paper presents cases of dirofilariasis lesions soft tissues face eyes. Purpose: to demonstrate possibility ultrasonic diagnosis face. Materials methods. Dirofilaria can affect face, eyes, mammary glands, buttocks. Patients complained swelling, indura...

A 3-month-old male red fox that was in contact with a Persian cat referred to the small animal hospital, Faculty of Veterinary Medicine, University of Tehran with multi-focal circular non-pruritic skin lesions and hair loss mainly on the head and extremities. A complete series of dermatologic tests such as Wood’s light examination, direct microscopic examination, and fungal culture were perform...