The Division of Biochemistry, Faculty of Chemistry, Opole University for more than 10 years has been involved in analysis of reactions catalysed by tyrosinase (monophenol oxidoreductase, L-dopa:O2, EC 1.14.18.1). This is a key enzyme in melanization process that catalyses its two first reactions: o-hydroxylation of tyrosine to 3,4-dihydroxyphenylalanine (DOPA) and oxidation of dopa to dopaquino...

glucose-6-phosphate dehydrogenase (g6pd) enzyme catalyses the first step in pentose phosphate pathway (conversion of glucose-6-phosphat to 6-phospho gluconat) which provides cells with pentoses and reduction power in the form of nadph. in the present study we have analyzed the g6pd gene mutations in 76 patients with a history of favism in khorasan province in iran. dna samples were analyzed for...

In 1937, Sir H. A Krebs first published the Citric Acid Cycle, a unidirectional cycle with carboxylic acids. The original concept of Cycle from Krebs’ 1953 Nobel Prize lecture illustrates degradation lactic acid to water, carbon dioxide and hydrogen. Here, we add heart lactate dehydrogenase•proton-linked monocarboxylate transporter 1 complex, connecting flow energy material. complex catalyses r...

Thyroid hormone (TH) receptors preferentially bind 3,5,3’-triiodothyronine (T3). Therefore the metabolism of thyroxine (T4) secreted by the thyroid gland in peripheral tissues, resulting in the production and degradation of receptor-active T3, plays a major role in thyroid function. The most important metabolic pathway for THs is deiodination. Another important pathway is sulfation, which is a ...