This paper addresses the use of neural networks as a metamodelling technique for discrete event stochastic simulation to reduce signi"cantly the computational burden involved by the simulations. A sophisticated computer model has been developed to anticipate the propagation of the green alga Caulerpa taxifolia in the northwestern Mediterranean sea. The simulation model provides reliable predict...

The purpose of the study is to evaluate the propagation of the green alga of tropical origin Caulerpa taxifolia (Vahl) C. Agardh in the north-western Mediterranean sea—introduced in 1984—by means of an algorithmic computer model. In order to take into account spatial interactions and anthropic dispersion or activities such as eradication and introduction of specific predators, the model is base...

Polysaccharides were extracted from Caulerpa lentillifera by treating with water and then purified by size-exclusion chromatography. The purified polysaccharides, termed SP1, were found to be sulfated xylogalactans with a molecular mass of more than 100 kDa. Adding SP1 to murine macrophage RAW 264.7 cells increased the production of nitric oxide (NO) in a dose-dependent manner. NO was found by ...