Primary cutaneous lymphomas (PCLs) are clonal Tor B-cell neoplasms, which originate in the skin. In recent years, mast cells were described as regulators of the tumor microenvironment in different human malignancies. Here, we investigated the role of mast cells in the tumor microenvironment of PCL. We found significantly increased numbers of mast cells in skin biopsies from patients with cutane...

OBJECTIVES To assess the degree to which preventive child health professionals (CHPs) identify and manage psychosocial problems among preschool children in the general population and to determine the association with parent-reported behavioral and emotional problems, sociodemographic factors, and mental health history of children. DESIGN The CHPs examined the child and interviewed the parents...

BACKGROUND Validated questionnaires can support the identification of psychosocial problems by the Preventive Child Health Care (PCH) system. This study assesses the validity and added value of four scoring methods used with the Strengths and Difficulties Questionnaire (SDQ) for the identification of psychosocial problems among children aged 7-12 by the PCH. METHODS We included 711 (of 814) c...

Resumen Background: The school-age versions of the ASEBA (Achenbach System of Empirically Based Assessment) incorporate the DSM-Oriented scales. These scales make it possible to quantify and normalize problems defi ned in the DSM. The objective was to study the incremental validity of the DSM-Oriented scales of the ASEBA inventories, the Child Behavior Checklist CBCL, completed by parents of ch...

Across development, maternal depression has been found to be a risk factor for youth psychopathology generally and youth depression specifically. Maternal Expressed Emotion (EE) has been examined as a predictor of outcome among youth with depression. The present study explored the associations between youth psychopathology and two predictors-maternal depression within the child's lifetime and m...

OBJECTIVE To test to what extent demographic variables and parent-reported problems and competencies in early adolescence predict incidence of mental health service use across a 5-year period in the general population. METHOD Data on parent-reported problem behavior (Child Behavior Checklist [CBCL]), gathered on 2,496 Dutch young adolescents, aged 10 to 12 years in 1989-1990, were linked to p...

OBJECTIVE Multiple psycho-social risk factors are common in children and adolescents in youth welfare, especially in residential care. In this survey study we assessed the prevalence of behavioral, emotional symptoms and mental disorders in a German residential care population. METHODS 20 residential care institutions including 689 children and adolescents (age 4 - 18 years; mean 14.4; SD = 2...

This study investigated whether parent-adolescent disagreement regarding adolescents' behavioral and emotional problems predicted adverse outcome. A Dutch sample of 15- to 18-year-olds was prospectively followed across a 4-year interval. The Child Behavior Checklist (CBCL: T. M. Achenbach, 1997) and Youth Self-Report (YSR; T. M. Achenbach, 1991b) were administered at initial assessment, and the...

BACKGROUND This study examines the diagnostic accuracy of the CBCL syndrome AS scales for predicting DSM-IV Attention Deficit-Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder with or without Conduct Disorder (ODD/CD). METHODS The sample included 370 children (187 probands and 183 siblings) participating in a family genetic study of attention and aggressive behavior problems. Un...

BACKGROUND The psychometric properties and cross-informant agreement of a German translation of the Screen for Child Anxiety Related Emotional Disorders (SCARED) were assessed in a clinical sample METHODS 102 children and adolescents in outpatient psychotherapy and their parents filled out the SCARED and Youth Self Report/Child Behaviour Checklist (YSR/CBCL). RESULTS The German SCARED showe...